小儿手足口病脑炎的MRI表现

目的:探讨小儿手足口病(hand-foot-mouth disease,HFMD)脑炎的MRI表现特征。方法:回顾性分析29例HFMD脑炎患儿临床及磁共振成像(MRI)资料,并与15例病毒性脑干脑炎进行比较。结果:HFMD脑炎临床症状重,意识障碍、呼吸循环衰竭发生率高(P<0.05),累及延髓的概率远大于病毒性脑干脑炎组,而发生在中脑的概率远小于病毒性脑干脑炎组(P<0.05),病变范围局限,呈稍长T1、长T2斑片状信号,DWI呈高信号,边界欠清。结论:小儿HFMD脑炎MRI表现具有特征性,MRI能明确脑炎脑损害的真实情况,对临床治疗提供可靠的影像依据。

MRI features of encephalitis in pediatric with hand-foot-mouth disease

Objective:To explore the MRI features of encephalitis in pediatric with hand-foot-mouth disease(HFMD).Methods:MRI and clinical data in 9 pediatric of HFMD encephalitis and 15 viral brainstem encephalitis cases were retrospectively analyzed and compared.Results:The clinical features of HFMD encephalitis were more serious,and the rates of unconsciousness,cardiorespiratory failure were higher than viral brainstem encephalitis.Most of HFMD encephalitis and viral brainstem encephalitis showed multiple and symmetrical lesions in brain stem.Lesions of HFMD encephalitis locating in medulla oblongata were far more than those of viral brainstem encephalitis,but lower in midbrain.The lesions were mostly patchy hypointense/sligtly hypointense on T1WI and hyperintense/slightly hyperintense onT2WI,T2-FLAIR and DWI with blurred border,some lesions were clear on T2-FLAIR or DWI.Conclusions:Characteristic features of encephalitis in pediatric with HFMD in MRI have high sensitivity in the diagnosis.MRI provide important information for differentiation,therapy and prognosis.