输卵管妊娠血β-hCG值与滋养细胞浸润输卵管肌层的关系

目的:探讨输卵管妊娠患者血β-hCG水平与滋养细胞浸润输卵管肌层的关系。方法:测定106例接受输卵管切除术的输卵管妊娠患者术前血β-hCG值。根据术后病理检查结果将患者分为A组(有滋养细胞浸润输卵管肌层)62例和B组(无滋养细胞浸润输卵管肌层)44例。计算病例的血β-hCG值百分位数,确定血β-hCG的阳性判断界限值。结果:106例患者血β-hCG值为(4890±763)IU/L。A、B两组间血β-hCG值的差异有显著性(P<0.01)。取3000IU/L为判断有无滋养细胞浸润输卵管肌层的血β-hCG界限值,诊断的准确率为93.40%,敏感度96.77%,特异度88.64%。结论:输卵管妊娠患者血β-hCG值水平与滋养细胞浸润输卵管肌层有明显的关系,血β-hCG值≥3000IU/L时,将发生滋养细胞浸润输卵管肌层。

Association of serum β- hCG levels with myosalpingeal invasion by trophoblast in tubal pregnancy.

Objective:To ascertain the relationship between myosalpingeal invasion by trophoblast and serum β-hCG levels in tubal pregnancy.Methods:Serum β-hCG was measured before the salpingectomy to 106 cases with tubal pregnancy.According to the results of biopsy,The cases were divided into two groups:Group A were 62 cases with myosalpingeal invasion by trophoblast,Group B were 44 cases with absence myosalpingeal invasion by trophoblast.Results:The mean serum β-hCG level for all cases was(4 890±763)U/L.The mean serum β-hCG level for group A cases was significantly higher than for Group B cases(P<0.01).The accuracy,sensitivity and specificity were 93.40%,96.77%,88.64%,respectively,with serum β-hCG levels of 3 000 U/L as the limited value in predicting myosalpingeal invasion by trophoblast.Conclusion:Myosalpingeal invasion by trophoblast correlate with serum levels of β-Hcg.Myosalpingeal invasion is highly likely when serum β-hCG levels over 3 000 U/L.