氧化压力与头发老化的相关性研究进展

氧化压力作为被普遍认可的人类老化的重要因素,在头发和头皮老化中也扮演了重要的角色。主要的脱发类型雄性激素脱发,压力型脱发和衰老型脱发均和氧化压力有不同程度的关系,而对于头发的灰白化,氧化压力是黑素细胞凋亡,黑色素生成减少的核心机制,毛囊黑素细胞和表皮黑素细胞相比经受更大的氧化压力;头屑和头皮敏感人群,尤其是油脂分泌旺盛导致的头屑和头皮敏感,脂质、氧化压力在其中扮演了重要角色。总而言之,氧化压力和头发头皮衰老的各种症状密切相关,在开发头发和头皮老化解决方案时,需要全面考虑抗氧化机制的应用。本文就氧化压力和脱发、头发灰白化,头屑和头皮敏感的关系等方面论述了国内外目前在该领域的研究进展。

Research Progress on the Correlation between Oxidative Stress and Hair Aging

Oxidative stress is most widely accepted mechanism on human aging,which also play an important role on hair or scalp skin aging.Endogenous or exogenous factors both lead the generation of oxidative stress.Androgenetic alopecia (AGA),hair loss due to stress or senescence are all correlated with oxidative stress to different extend.For hair greying,oxidative stress is the core mechanism which will cause hair follicle melanocyte apoptosis,or damage of its stem cell,then decrease the capability of melanin production and transferring.For dandruff or sensitive scalp skin population,lipid oxidation and its downstream signaling pathway can exacerbate the conditions.In summary,Oxidative stress plays important role in different hair aging symptoms.Therefore,anti-oxidant design is crucial when considering solve the scalp skin problems.In the article,it’s reviewed about what’s oxidative stress,what’s the relationship between it and alopecia/hair greying/dandruff and sensitive scalp skin.