柠檬烯对小白鼠中枢神经系统的影响

目的观察柠檬烯对小鼠中枢神经系统作用。方法用Y型电刺激迷宫器，40伏特的电流电刺激小鼠足趾，观察记录柠檬烯对小鼠疼痛逐避反应时间（秒）的影响、观察柠檬烯增强颅通定对电刺激小鼠足趾的镇痛作用，记录电刺激阅电压（伏特）；观察柠檬烯拮抗戊巴比妥钠催眠作用，记录入睡时间和睡眠时间（min）。结果柠檬稀能明显抑制小鼠疼痛逃避反应时间；增强颅通定镇痛作用．提高电刺激阅电压；缩短戊巴比妥钠催眠时间。结论柠檬烯有镇痛作用和促进神经中枢雏持觉醒作用。

The Influence of Limonene on Central Nervous System of Mice

OBJECTIVE To study the effect of Limonene electric Current on the central nervous system of mice.METHODS By Y-type electrified grid maze with 40V(electrcity)to stimulate the mice feet,record the pain-escaping response time(seconds).Inspect the affection of Limonene to the analgestic effect of Rotundine and check the pain shreshold of stimulating electric voltage.Observe the antagnising effect of Limonene to the hypnotic dosage of sodium pentobarbital,write down latency time and sleeping time.RESULTS Limonene could significally inhibite mice pain-escape response (in low dosage group),slightly strengthen the analgestic effect of Rotundine increase the threshold Voltage Volue.Limonene shorten the sleeping time induced by sodium pentobarbital.CONCLUSION Limonene has analgestic effect and keep the mice in the awaken state.