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核苷(酸)类似物抗乙型肝炎病毒应用进展及耐药新认识
引用本文:周东方,周俊英,赵彩彦. 核苷(酸)类似物抗乙型肝炎病毒应用进展及耐药新认识[J]. 国外医学:内科学分册, 2007, 34(10): 602-604,609
作者姓名:周东方  周俊英  赵彩彦
作者单位:河北医科大学第三医院感染科 河北石家庄050051
摘    要:核苷(酸)类似物是目前临床上治疗乙型肝炎的重要药物,但应用过程中可出现乙型肝炎病毒的变异,从而发生耐药。本文就核苷(酸)类似物在乙型肝炎治疗方面的进展以及病毒耐药的新认识作一综述。

关 键 词:核苷(酸)类似物  乙型肝炎病毒  耐药
文章编号:1004-2369(2007)10-0602-03
修稿时间:2007-03-182007-06-28

The progress of treating with nucleos(t)ide analogs for hepatitis B and new realization of antivitral resistance
ZHOU Dong-fang,ZHOU Jun-ying,ZHAO Cai-yan. The progress of treating with nucleos(t)ide analogs for hepatitis B and new realization of antivitral resistance[J]. Foreign Medical Sciences(Section of Internal Medicine), 2007, 34(10): 602-604,609
Authors:ZHOU Dong-fang  ZHOU Jun-ying  ZHAO Cai-yan
Affiliation:Department of Infectious The Third Hospital, Hebei Medical University, Shijiazhuang 050051, China
Abstract:Currently,more and more nucleos(t) ide analogs are appearing as therapeutic options in the treatment of chronic hepatitis B(CHB).But prolonged therapy can develope antiviral resistance.This review summarizes the progress of the therapy with nucleos(t)ide analogs for hepatitis and new realization of viral resistance.
Keywords:Nucleos(t)ide analogs  Hepatitis B virus  Resistance
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