老年患者烤瓷冠修复后龈沟液成分的变化

目的：探讨老年患者烤瓷冠修复后龈沟液成分的变化.方法：选取近两年在我院口腔修复科就诊的60岁以上,需进行烤瓷单冠修复的患者50例为受试对象,其中男25性名,女性25名,年龄60-69岁,常规牙周洁治后采用钴铬合金烤瓷单冠修复,分别在修复前以及修复后1,2个月检测基牙龈沟液的分泌量以及白细胞介素1β,碱性磷酸酶和肿瘤坏死因子α水平.结果：修复后1个月基牙龈沟液分泌量以及白细胞介素1,碱性磷酸酶和肿瘤坏死因子α水平明显高于修复前（分别为龈沟液分泌量：0.18±0.012 VS 0.46±0.024＊＊；白细胞介素1：6.42±0.87 VS 27,73±7.62＊＊；碱性磷酸酶：34.27±6.41VS 48.32±5.49＊；肿瘤坏死因子α：0.88±0.052 VS1.75±0.45＊＊）.修复后2个月基牙龈沟液分泌量和白细胞介素1仍显著高于修复前（分别为龈沟液分泌量：0.18±0.012 VS 0.31±0.019＊＊；白细胞介素1：6.42±0.87 VS 19.45±6.04＊＊）,但碱性磷酸酶和肿瘤坏死因子α水平与修复前比较无显著性差异（碱性磷酸酶：34.27±6.41 VS 38,66±8.92；肿瘤坏死因子α：0.88±0.052 VS l.02±0.61）.结论：钴铬合金烤瓷单冠修复可使老年患者龈沟液分泌量增加,相关炎性因子表达增高.

Effect of porcelain-fused-to-metal crown on ingredient of gingival crevicular fluid in gerontal patients

Objective： To investigate the ingredient changes of gingival crevicular fluid after treated with porce- lain-fused-to-metal crown in elderly patients. Method： Fifty patients who needed porcelain-fused-to-metal crown restora- tion in our department in recent two years were randomly selected, including 25 male and 25 female with ages from 60-69 years old. After periodontal treatment, all patients were treated with porcelain-fused-to-metal crown. Then gross secretory volume of gingival crevicular fluid, IL-1, ALP and TNF-αlevels were detected before and after treatment to analyze the ef- fect of porcelain-fused-to-metal crown on ingredient of gingival crevicular fluid in elderly patients. Results： One month af- ter restoration, gross secretory volume of gingival crevicular fluid, IL-1, ALP and TNF-αlevels increased significantly, （gross secretory volume of gingival crevicular fluid： 0. 1 8±0.012 VS 0.46±0.024＊＊; IL-1： 6.42±0.87 VS 27.73±7.62; ALP： 34.27±6.41 VS 48.32±5.49＊; TNF-α： 0.88±0.052 VS 1.75±0.45）; 2 month after restoration, only gross secretory volume of gingival crevicular fluid and IL-1 level were significantly higher than pretreatment, （gross secretory volume of gingival crevicular fluid： 0.18±0.012 VS 0.31 ＋0.019; IL-1 6.42＋0.87 VS 19.45±6.04＊＊; ALP： 34.27±6.41 VS 38.66±8.92; TNF-α： 0.88±0.052 VS 1.02±0.61）. Conclusion： Porcelain-fused-to-metal crown could promote gingival crevicular fluid secretion, and IL-1, ALP and TNF-Mevels in gingival crevicular fluid of elderly patients.