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氨来咕诺糊剂治疗顽固性口腔扁平苔藓的可行性初探
引用本文:周威,梁莉,张磊,陈明,张琳. 氨来咕诺糊剂治疗顽固性口腔扁平苔藓的可行性初探[J]. 中华老年口腔医学杂志, 2013, 0(3): 158-159
作者姓名:周威  梁莉  张磊  陈明  张琳
作者单位:[1]解放军第309医院口腔科,北京100091 [2]第三军医大学大坪医院口腔科,重庆400000
摘    要:目的:初步探讨采用氨来咕诺糊剂治疗顽固性糜烂型口腔扁平苔藓的可行性.方法:5例顽固性糜烂型口腔扁平苔藓患者,采用局部涂用氨来呫诺糊剂1周,观察其初步疗效和可能发生的不良反应.结果:1例治疗后显效,2例有效,2例无效.无不良反应发生.结论:氨来咕诺糊剂治疗顽固性糜烂型OLP有一定疗效趋势.

关 键 词:氨来咕诺糊剂  局部治疗  糜烂型  口腔扁平苔藓

The preliminary efficacy of topical application of amlexanox paste in treatment of refractory erosive oral lichen planus
ZHOU Wei,LIANG Li,ZHANG Lei,CHEN Ming,ZHANG Lin. The preliminary efficacy of topical application of amlexanox paste in treatment of refractory erosive oral lichen planus[J]. Chinese JOurnal of Geriatric Dentistry, 2013, 0(3): 158-159
Authors:ZHOU Wei  LIANG Li  ZHANG Lei  CHEN Ming  ZHANG Lin
Affiliation:. (Department of Stomatology, the 309th hospital of Chinese PLA, Beijing 100091, China)
Abstract:Objectives: The aim of the study was to observe the preliminary efficacy ofamlexanox paste by topical appli- cation in treatment of refractory erosive OLP. Methods : Five patients with refractory erosive OLP were enrolled and treat- ed with amlexanox paste 4 times per day for two weeks. We observed the efficacy and side-effects. Results: The treatment was ineffective for 2 patients, 2 patients had symptomatic improvement, 1 patients were healed. No severe adverse drug re- actions had been observed. Conclusion: Topical application of amlexanox paste was effective in the treatment of refracto- ry erosive OLP and had no adverse effects, but more clinical trials to prove it should be performed.
Keywords:amlexanox paste  topical application  erosive oral lichen planus  refractory
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