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银杏叶制剂、丹参对急性肾功能衰竭家兔血液流变学的影响
引用本文:刘久波,陈林,杨道华,易建华,杨青山,朱礼国,李茂玉.银杏叶制剂、丹参对急性肾功能衰竭家兔血液流变学的影响[J].微循环学杂志,2002,12(3):3-5.
作者姓名:刘久波  陈林  杨道华  易建华  杨青山  朱礼国  李茂玉
作者单位:1. 湖北省郧阳医学院附属太和医院微循环科,十堰,442000
2. 湖北省郧阳医学院附属太和医院药学部,十堰,442000
3. 湖北省郧阳医学院附属太和医院病理科,十堰,442000
4. 湖北省郧阳医学院附属太和医院神经疾病研究所,十堰,442000
摘    要:目的 :探讨银杏叶制剂 (GbE)、丹参对实验性急性肾功能衰竭(ARF)兔血液流变学、肾功能的影响。方法 :用 5 0 %的甘油 10ml/kg行兔后肢肌肉加压注射 ,建立ARF动物模型 ,观察不同时相血液流变学、肾功能 (血Cr、BUN)的改变 ,并给予GbE、丹参注射液处理。结果 :ARF组肾功能明显下降 ,血液流变学指标明显异常。GbE组、丹参组动物血液流变学指标明显改善 ;肾功能得到保护。结论 :GbE、丹参对甘油所致ARF家兔的血液流变性、肾功能有明显的保护作用

关 键 词:银杏叶制剂  丹参  急性肾功能衰竭  血液流变学  肾功能  
修稿时间:2002年4月1日

Effects of GhE and Tanshin on Hemorrheological Indexes in Acute Renal Failure in Rabbits
Liu Jiubo,Cheng Lin,Yang Daohua,et al/.Effects of GhE and Tanshin on Hemorrheological Indexes in Acute Renal Failure in Rabbits[J].Chinese Journal of Microcirculation,2002,12(3):3-5.
Authors:Liu Jiubo  Cheng Lin  Yang Daohua  /
Institution:Liu Jiubo,Cheng Lin,Yang Daohua,et al/Department of Microcirculation,Affiliated Taihe Hospital of Yunyang medical College,Shiyan 442000
Abstract:Objective: To observe the effects of GbE and Tanshin on hemorheological and renal function(blood Cr?BUN) indexes in acute renal failure(ARF) in rabbits.Method: The models of ARF were established by high pressure injection of 50% glycerine into muscle of hind legs in rabbits.The details of hemorrhology,Blood Cr?BUN were observed before and after ARF,as well as the treatment.Results: The renal function remarkably declined in ARF,meanwhile,hemorrheological indexes were evidently abnormal.On the contrary,in the GbE+ARF and the Ts+ARF,the hemorheological indexes were obviously better than in the ARF,Furthermore,the renal function was improved.Conclusion: The GbE and Tanshim can prevent hemorrheological indexes on ARF by injection of glycerine in rabbites.
Keywords:Ginkgo biloba Extraction(GbE)  Tanshin(Ts)  Acute renal failure(ARF)  Hemorrheology  Renal function  Rabbits
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