| 高-低氧放疗与低氧放疗对食管癌疗效的对比研究 |
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| 引用本文： | 孙衍伟,曾琴琴,侯仕彩,丁兆军,周嘉云,安永恒,孟令新.高-低氧放疗与低氧放疗对食管癌疗效的对比研究[J].实用全科医学,2011(10):1540-1541. |
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| 作者姓名： | 孙衍伟 曾琴琴 侯仕彩 丁兆军 周嘉云 安永恒 孟令新 |
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| 作者单位： | 山东省日照市人民医院肿瘤科;青岛大学医学院附属医院肿瘤中心; |
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| 摘 要： | 目的比较高-低氧放射治疗与低氧放射治疗食管癌的近远期疗效及毒副反应。方法将68例欲接受根治性放疗的食管癌患者随机分入高-低氧组和低氧组。所有患者均采用6 MV X线照射,DT 1.8～2.0 Gy/次,每周5次。高-低氧组在放疗时先后吸入高、低浓度氧,低氧组在放疗过程中吸入低浓度氧。观察两组患者的总有效率,1年、3年、5年生存率,放疗急性反应及晚期并发症。结果高-低氧组有效率高于低氧组（81.3%VS 54.5%,χ2=5.2976,P=0.0214）,两组1年生存率无明显差异（71.9%VS 57.6%,χ2=1.4529,P=0.2281）,但3年及5年生存率高-低氧组均高于低氧组（53.1%VS 27.3%,χ2=4.5241,P=0.0334;34.4%VS 12.1%,χ2=4.5324,P=0.0333）。两组的放疗急性反应及晚期并发症差异无统计学意义。结论高-低氧放射治疗食管癌在总有效率及3年、5年生存率方面均优于低氧放疗,放疗毒副反应无明显增加。
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| 关 键 词： | 食管癌 氧 放射治疗 |
The Contrast of High-Low Oxygen Radiotherapy and Low Oxygen Radiotherapy in Patients with Esophageal Carcinoma |
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| SUN Yan-wei,ZENG Qin-qin,HOU Shi-cai,et al..The Contrast of High-Low Oxygen Radiotherapy and Low Oxygen Radiotherapy in Patients with Esophageal Carcinoma[J].Applied Journal Of General Practice,2011(10):1540-1541. |
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| Authors: | SUN Yan-wei ZENG Qin-qin HOU Shi-cai |
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| Institution: | SUN Yan-wei,ZENG Qin-qin,HOU Shi-cai,et al.Department of Oncology,People's Hospital of Rizhao,Rizhao 276826,Shandong,China |
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| Abstract: | Objective To investigate the clinical effects and side effects of high-low oxygen radiotherapy and low oxygen radiotherapy in patients with esophageal carcinoma.Methods From May 2004 to January 2006,68 cases of esophageal carcinoma were randomly divided into high-low oxygen group and low oxygen group.Patients in the former received radiation with high-low oxygen inspiring,while those in the latter were given radiation with low concentration oxygen inspiring.Radiation was administered with 6 MV X-rays,1.8-2.... |
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| Keywords: | Esophageal Neoplasms Oxygen Radiotherapy |
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