| 血清载脂蛋白B与冠脉病变程度的相关性研究 |
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| 引用本文： | 冯燕娴,汤凤英,石增刚,桑更生.血清载脂蛋白B与冠脉病变程度的相关性研究[J].实用全科医学,2011(9):1340-1342. |
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| 作者姓名： | 冯燕娴 汤凤英 石增刚 桑更生 |
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| 作者单位： | 安徽省蚌埠市第三人民医院心内科; |
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| 基金项目： | 安徽省蚌埠市科技局2009年科技项目[2009(68)号] |
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| 摘 要： | 目的探讨血清载脂蛋白B（ApoB）水平与颈动脉斑块、冠状动脉粥样病变及其严重程度的关系。方法248例行冠脉造影检查的住院患者根据冠脉造影结果分为单支病变组（59例）、多支病变组（107例）和对照组（82例），比较血清ApoB水平在各组中的变化，分析血清ApoB水平与颈动脉斑块、冠脉狭窄严重程度的相关性。结果①冠心病单支病变组血清ApoB（1．09±0．25g／Lvs0．69±0．18g／L，P〈0．05）和多支病变组血清ApoB（1．99±0．11g／Lvs0．69±0．18g／L，P〈0．01）显著高于对照组，且多支病变组血清ApoB水平较单支病变组差异有统计学意义（1．09±0．25g/L vs1．99±0．11g／L，P〈0．05）；②冠心病单支病变组和多支病变组颈动脉易损斑块的发生率（20．3％、23．4％VS7．3％，P〈0．05）与对照组相比明显增高；③血清ApoB水平与冠心病颈动脉易损斑块发生率（r=0．482，P〈0．05）呈显著正相关，与冠脉积分（r=0．563，P〈0．05）亦呈显著正相关。结论血清ApoB水平反映了动脉粥样硬化的程度，与冠脉病变严重程度密切相关。
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| 关 键 词： | 载脂蛋白B 颈动脉斑块 冠状动脉病变程度 |
Correlation between Apolipoprotein B and Severity of Coronary Artery Stenosis |
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| FENG Yan-xian,TANG Feng-ying,SHI Zeng-gang,et al..Correlation between Apolipoprotein B and Severity of Coronary Artery Stenosis[J].Applied Journal Of General Practice,2011(9):1340-1342. |
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| Authors: | FENG Yan-xian TANG Feng-ying SHI Zeng-gang |
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| Institution: | FENG Yan-xian,TANG Feng-ying,SHI Zeng-gang,et al.Department of Cardiology,Bengbu Third People's Hospital,Bengbu 233000,Anhui,China |
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| Abstract: | Objective To investigate the correlation between apolipoprotein B(ApoB) and carotid artery plaque,the extent and severity of coronary artery lesion.Methods Two hundred and forty-eight patients underwent coronary angiography(CAG) were enrolled.The patients were divided into three groups by the results of CAG:control group(n=82),single-vessel group(n=59) and multi-vessel group(n=107).Plasma ApoB were measured in every patients,while the characters of carotid artery plaque were investigated by ultrasound.The r... |
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| Keywords: | Apolipoprotein B Carotid artery plaque Coronary artery stenosis |
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