| MPV和AR与非ST段抬高ACS患者不良预后的相关性 |
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| 引用本文： | 许光银.MPV和AR与非ST段抬高ACS患者不良预后的相关性[J].实用全科医学,2011(9):1452-1453. |
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| 作者姓名： | 许光银 |
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| 作者单位： | 山东省聊城市第三人民医院检验科; |
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| 摘 要： | 目的探讨平均血小板体积（MPV）和阿司匹林抵抗（AR）与非sT段抬高的急性冠脉综合征（ACS）患者不良心血管事件发生的相关性。方法197例非sT段抬高的ACS患者，每日口服阿司匹林100mg〉4周，检测由ADP诱导的血小板聚集率（PAG）和Sysmex XT-1800i检测的MPV，根据PAG和MPV将患者分为4组：①MPV正常不伴阿司匹林抵抗组（对照组）；②MPV正常伴阿司匹林抵抗组；③MPV升高不伴阿司匹林抵抗组；④MPV升高伴阿司匹林抵抗组，随访观察4组主要不良事件（心源性死亡、心肌梗死、血运重建）发生的比率并进行比较。结果在197例非ST段抬高的ACS患者中，4组不良事件发生率分别为12．0％、18．6％、23．4％和62．5％，其中组4（MPV升高伴阿司匹林抵抗组）与组1（对照组）比较，不良事件发生比率明显增高（62．5％VS12．0％，P〈0．0001）。结论MPV升高和AR与非sT段抬高的ACS患者不良心血管事件的发生呈正相关．它是非ST段抬高的ACS患者的重要危险因素和独立预测因子。
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| 关 键 词： | 血小板平均体积 阿司匹林抵抗 急性冠脉综合征 血小板聚集率 |
Association of Mean Platelet Volume and Aspirin Resistance with Poor Prognosis in Non-ST-Segment Elevated Acute Coronary Syndromes |
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| XU Guang-yin.Association of Mean Platelet Volume and Aspirin Resistance with Poor Prognosis in Non-ST-Segment Elevated Acute Coronary Syndromes[J].Applied Journal Of General Practice,2011(9):1452-1453. |
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| Authors: | XU Guang-yin |
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| Institution: | XU Guang-yin.Department of Laboratory Science,Liaocheng NO.3 People's Hospital,Liaocheng 252000,Shandong,China |
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| Abstract: | Objective To investigate aspirin resistance and mean platelet volume(MPV) in patients with non-ST-segment elevation acute coronary syndromes related adverse clinical cardiovascular events.Methods 197 patients with non-ST-segment elevation acute coronary syndromes took aspirin 100 mg/d for more than four weeks.Platelet aggregation function(PAG) was induced with adenosins disphosphate(ADP) and mean platelet volume was detected with Sysmex XT-1800i.The patients with acute coronary syndromes were divided into M... |
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| Keywords: | Mean platelet volume Aspirin resistance Acute coronary syndromes Platelet aggregation |
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