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依达拉奉对血塞通治疗急性脑梗死患者凝血纤溶系统的影响
引用本文:伍德生,李强. 依达拉奉对血塞通治疗急性脑梗死患者凝血纤溶系统的影响[J]. 实用全科医学, 2011, 0(9): 1347-1347,1491
作者姓名:伍德生  李强
作者单位:安徽省蚌埠医学院第一附属医院急诊内科;安徽省蚌埠医学院第一附属医院神经内科;
摘    要:目的探讨依达拉奉联合血塞通对急性脑梗死患者凝血纤溶系统的影响。方法将79例急性脑梗死患者随机分为治疗组和对照组,对照组39例,给予注射用血塞通每日0.4g静脉滴注,治疗组40例,在对照组用药基础上加用依达拉奉注射液每日30mg静脉滴注,疗程14d。治疗前及治疗后第14天分别测定患者的凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)和纤维蛋白原(Fg),并进行美国国立卫生研究院卒中量表(NIHSS)评分。结果治疗第14天,治疗组血赡浓度及NIHSS评分较对照组明显降低(P〈0.05),血浆PT、APTT和TT值两组差异无统计学意义(P〉0.05)。结论依达拉奉对血塞通治疗急性脑梗死患者血浆胛、APTT和TT值无明显影响,但能够降低患者血浆Fg的浓度,进一步改善神经功能缺损症状。

关 键 词:急性脑梗死  依达拉奉  血塞通  C反应蛋白  纤维蛋白原

Effect of Edaravone on Coagulation and Fibrinolysis System of Acute Cerebral Infarction Patients Receiving Panax Notoginoside Injection
WU De-sheng,LI Qiang. Effect of Edaravone on Coagulation and Fibrinolysis System of Acute Cerebral Infarction Patients Receiving Panax Notoginoside Injection[J]. Applied Journal Of General Practice, 2011, 0(9): 1347-1347,1491
Authors:WU De-sheng  LI Qiang
Affiliation:WU De-sheng,LI Qiang.Department of Emergency Medicine,the First Affiliated Hospital of Bengbu Medical College,Bengbu 233004,Anhui,China
Abstract:Objective To evaluate the effects of Edaravone with Panax Notoginoside Injection on the coagulant and fibrinolytic function of patients with acute cerebral infarction(ACI).Methods Seventy nine patients with ACI were randomly divided into treatment group(Edaravone injection plus Panax Notoginoside Injection) and control group(Panax Notoginoside Injection).The levels of plasma PT,APTT,TT and Fg were measured and NIH Stroke Scales(NIHSS) were evaluated before and after the treatment.Results After the treatment...
Keywords:Acute cerebral infarction  Edaravone  Panax Notoginoside Injection  C-reactive protein  Fibrinogen  
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