Effects of some DSIP peptide analogs on rat sleep for intraventricular infusion |
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| Authors: | S Inoue M Kimura-Takeuchi V M Koval'zon V N Kalikhevich S I Churkina |
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| Institution: | (1) Institute of Medical and Stomatological Engineering, Medical and Stomatological University, Tokyo;(2) A. N. Severtsov Institute of Evolutionary Morphology and Ecology of Animals, Russian Academy of Sciences, Moscow;(3) Research Institute of Chemistry, State University, St. Petersburg |
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| Abstract: | Peptide D-AIa2]DSIP markedly increases the representation of NREM and REM sleep delayed by several hours from the onset of infusion and
lasting after the infusion till the end of the 12-hour night period in a chamber. Peptide D-Tyr1]DSIP increases NREM sleep during hours IV and XI of recordings. Analogs of these peptides have no noticeable effects.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N
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1, pp. 56–58, January, 1994
Presented by I. P. Asnmarin. Member of the Russian Academy of Medical Sciences |
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| Keywords: | DSIP peptide sleep rats |
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