| 树突状细胞与调节性T细胞相互作用研究进展 |
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| 引用本文： | 黄立锋,姚咏明,盛志勇.树突状细胞与调节性T细胞相互作用研究进展[J].中国病理生理杂志,2008,24(3):610-616. |
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| 作者姓名： | 黄立锋 姚咏明 盛志勇 |
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| 作者单位： | 解放军总医院第一附属医院全军烧伤研究所基础部，北京 100037 |
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| 基金项目： | 国家重点基础研究发展计划(973计划)
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国家自然科学基金 |
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| 摘 要： | 树突状细胞(dendritic cells,DCs)是1类复杂且具有异质性、可塑性的细胞,系"专职的"抗原提呈细胞(antigen presenting cells,APCS),也是体内主要的可激活"初始型"免疫反应的细胞.
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| 关 键 词： | 树突细胞 调节性T细胞 免疫调节 |
| 文章编号： | 1000-4718(2008)03-0610-07 |
| 收稿时间： | 2006-9-4 |
| 修稿时间： | 2006年9月4日 |
Recent advances in the correlations between dendritic cells and regulatory T cells |
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| HUANG Li-feng,YAO Yong-ming,SHENG Zhi-yong.Recent advances in the correlations between dendritic cells and regulatory T cells[J].Chinese Journal of Pathophysiology,2008,24(3):610-616. |
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| Authors: | HUANG Li-feng YAO Yong-ming SHENG Zhi-yong |
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| Institution: | Basic Research Department of Burns Institute, First Hospital Affiliated to PLA General Hospital, Beijing 100037, China. E-mail:c_ff@sina.com |
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| Abstract: | Dendritic cells (DCs), representing a heterogenous population of professional antigen-presenting cells, are the initiators and modulators of the immune responses. Studies indicate that regulatory T cells contribute to immune nullipotency and immune suppression via cell-cell contact or cytokine secretion. These two kinds of cells may be valuable tools for modulating immunity in the setting of auto-immunity, cancer, chronic viral infections and graft rejection, etc. Here we discuss the current knowledge on the functions of regulatory T cells and denditic cells-based immunoregulation and the applications. |
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| Keywords: | Dendritic cells Regulatory T cells Immunoregulation |
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