经阴道和腹腔镜行良性卵巢肿瘤切除术患者免疫功能改变的临床意义

目的 探讨良性卵巢肿瘤经阴道和腹腔镜行切除术对人体免疫功能改变的影响.方法 应用免疫透射比浊法测定对患者经阴道(60例)和腹腔镜(60例)手术前、手术后12 h静脉血免疫球蛋白G(IgG)、免疫球蛋白A(IgA)、免疫球蛋白M(IgM)和C-反应蛋白(CRP)水平,并对结果进行统计学处理.结果 腹腔镜组与经阴道组术后IgG、IgA、IgM和CRP结果比较差异有统计学意义(P<0.01),表明两种手术方式对机体免疫功能的影响程度明显不同.结论 女性良性卵巢肿瘤经阴道行切除术对机体免疫功能影响小,具有手术时间短,创口小,在患者体表不留下疤痕等优点,患者易于接受,值得在临床广泛推广.

Clinical significance of changes in immune function in patients with benign ovarian tumors treated by transvaginal and laparoscopic resection

Objective To investigate the influence of transvaginal and laparoscopic surgery for treating benign ovarian tumors on immune function.Methods The full-automatic biochemical analyzer was used to detect immunoglobulin G（IgG）,immunoglobulin A（IgA）,immunoglobulin M（IgM） and C-reactive protein（CRP） in 60 cases of transvaginal surgery and 60 cases of laparoscopic surgery before operation and after 12 h of operation and the results were performed the statistical analysis.Results The detection results of IgG,IgA,IgM and CRP after operation had statistical difference between the laparoscopic group and the transvaginal group（P0.01）,showing that the influencing degree of these two surgical procedures on immune function was significantly different.Conclusion Transvaginal resection of female benign ovarian tumor has little effect on immune function,with the advantages of shorter operative time,small wound without leaving scars in the body surface,which is easily accepted by patients and worthy of popularization in clinic.