速效救心丸治疗急性冠状动脉综合征的疗效观察

目的观察氯吡格雷联合速效救心丸对急性冠状动脉综合征（ACS）患者的临床疗效。方法将2010年1月-2011年12月收治的ACS患者随机选取97例后随机分为治疗组（氯吡格雷联合速效救心丸组，48例）和对照组（氯吡格雷组，49例），以1个月为1个疗程，1个疗程后观察临床疗效、心绞痛发作频率、ST段位移的变化及不良反应的发生情况。结果1个疗程后，治疗组总有效率为79．2％，对照组总有效率为51．0％，两组间比较差异有统计学意义（P〈0．05）。两组在治疗后心绞痛发作频率、ST段位移均明显改善，与治疗前比较，差异有统计学意义（P〈0．05）；在治疗后，两组间比较差异有统计学意义（P〈0．05），治疗组临床疗效、ST段位移变化优于对照组。结论氯吡格雷与速效救心丸联用治疗ACS比单用氯吡格雷疗效好，值得临床推广应用。

Observation of the Clinical Effect of Suxiao Jiuxin Pills on Patients with Acute Coronary Syndrome

Objective To observe the clinical effect of clopidogrel combined with Suxiao Jiuxin Pills on patients with acute coronary syndrome （ACS）. Methods Ninety-seven patients with ACS diagnosed between January 2010 and December 2011 were divided into the treatment group （treated with clopidogrel combined with Suxiao Jiuxin Pills） （n=48） and the control group （treated with single clopidogrel） （n=49）. One month was regarded as a treatment course. After one month, we observed the clinical effect, heart attacks frequency, ST segment changes and adverse reactions for the patients. Results The total effective rate was 79.2% in the treatment group and was 51.0% in the control group. There was significant difference between the two groups （P 〈 0.05）. Heart attacks frequency and ST segment were reduced significantly in both the two groups after treatment （P 〈 0.05）. The curative effect in the treatment group was significantly better than that in the control group after treatment （P 〈 0.05）. Conclusion Clopidogrel combined with Suxiao Jiuxin Pills have a better clinical effect in the treatment of ACS than single clopidogrel.