缺血性脑血管病颈动脉狭窄危险因素分析

目的基于全脑数字减影血管造影（DSA）分析缺血性脑血管病颈动脉狭窄的危险因素。方法纳入2011年6月-2013年9月行DSA检查的缺血性脑血管病患者312例，用多因素logistic回归分析方法对缺血性脑血管病颈动脉狭窄的危险因素进行分析。结果患者中脑梗死271例，短暂性脑缺血发作41例。颈动脉狭窄程度≥50％者149例，狭窄程度〈50％者163例。年龄（OR=1．037，P=0．000）及冠心病（OR=4．121，P=0．031）为缺血性脑血管病颈动脉狭窄的独立危险因素。结论颈动脉狭窄在缺血性脑血管病中较常见，年龄和冠心病为其独立危险因素。对危险因素的识别和积极控制有助于缺血性脑血管病的二级预防。

Risk Factors for Carotid Stenosis in Patients with Ischemic Cerebrovascular Disease

Objective To analysis the risk factors for carotid stenosis in patients with ischemic cerebrovascular disease based on digital subtraction angiography. Methods A total of 312 patients diagnosed with ischemic cerebrovascular disease who underwent digital subtraction angiography from June 2011 to September 2013 were selected. The risk factors of carotid stenosis were analysised by multivariate logistic regression analysis. Results In 312 patients, 271 were with cerebral infarction and 41 were transient ischemic attack patients. There were 149 patients in carotid stenosis group （stenosis degree ≥ 50%） and 163 patients in control group （stenosis degree 〈 50%）. The age （0R=1.037, P=0.000） and coronary heart disease （OR=4.121, P=0.001） were independent risk factors of carotid stenosis with ischemic cerebrovascular disease. Conclusions Carotid stenosis is common in ischemic cerebrovascular disease. Age and coronary heart disease were the independent risk factors. The recognition and control of these risk factors are in favor of secondary prevention of ischemic cerebrovascular disease.