镍铬合金烤瓷修复体拆除前后患者尿镍铬含量的检测与评估

目的探讨镍铬合金烤瓷修复体是否会对人体尿液中的镍、铬含量造成影响。方法选择要求拆除原镍铬烤瓷修复体的患者86例,于修复体拆前、拆后1个月,分别检测患者尿镍、铬含量,并按年龄、性别、修复体数目、修复体戴入时间以及修复体有无金属暴露等进行分组分析。结果 86例患者在镍铬烤瓷修复体拆除前后的尿镍含量分别为(3.52±3.05)μg/L、(3.31±3.28)μg/L,差异无统计学意义(P>0.05);拆除前后的尿铬含量分别为(0.81±0.54)μg/L、(1.34±1.15)μg/L,差异亦无统计学意义(P>0.05)。患者的尿镍、铬含量与年龄、性别、修复体的数量、修复时间以及有无金属暴露等均无明显的相关性(P>0.05)。结论镍铬合金烤瓷修复体所释放的镍、铬离子量微小,短期内不足以对人体尿液中的镍、铬含量造成影响。

Detection and assessment of the nickel and chromium levels in urine in patients before and after removal of nickel-chromium alloy porcelain-fused-to-metal crown restoration

Objective To investigate whether the nickel-chromium alloy porcelain-fused-to-metal crown（PFM） have effect on the nickel and chromium levels in urine.Methods Eighty-six patients were selected for the study,which suspected that nickel-chromium alloy PFM may affect their health and therefore came to hospital to ask for removal of prosthesis.The urine levels of nickel and chromium in 86 patients were detected before and after removal of nickel-chromium alloy PFM restoration.In addition,the urine levels of nickel and chromium in these patients were analyzed according to their age,gender,the number and duration of PFM restorations,and whether the metal exposed or not in restoration.Results There were no statistical difference between results of urine levels of nickel and chromium in patients before and after removal of the nickel-chromium alloy PFM restoration（P0.05）.In addition,the urine levels of nickel and chromium in patients have nothing to do with gender,age,the number and duration of PFM restorations,and whether the metal exposed or not in restoration（P0.05）.Conclusion The amount of nickel and chromium released from nickel-chromium alloy PFM is small,which would not effect the urine levels of nickel and chromium in human.