Relationship between the baroreceptor reflex and the variability of arterial pressure and of the heart beat period in rats with arterial hypertension

The relationship between depression of the cardiochronotropic component of the baroreceptor reflex and arterial pressure and heart beat variabilities was investigated in normotensive rats and rats with renal hypertension (one kidney — one clamp). In the hypertensive rats, the arterial pressure and heart rate were both increased and more variable, while the cardiochronotropic component of the baroreceptor reflex was depressed. No cause-effect relationship between baroreceptor reflex attenuation and increased variability of hemodynamic parameters was found in this rat model of arterial hypertension. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No. 5, pp. 474–476, May, 1995 Presented by B. I. Tkachenko, Member of the Russian Academy of Medical Sciences