| 支气管哮喘患儿血清SOD、ET和NO水平检测的临床意义 |
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| 引用本文： | 高长龙.支气管哮喘患儿血清SOD、ET和NO水平检测的临床意义[J].淮海医药,2004,22(6):457-458. |
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| 作者姓名： | 高长龙 |
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| 作者单位： | 江苏省连云港市第一人民医院,儿科,222002 |
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| 摘 要： | 目的 探讨支气管哮喘患儿血清超歧过氧化物酶 (SOD)、内皮素 (ET)和一氧化氮 (NO)水平的变化。方法 分别应用放免法和化学法检测 36例支气管哮喘患儿血清 SOD、ET和 NO水平 ,并与 35例正常健康儿作比较。结果 支气管哮喘患儿血清 SOD水平显著低于正常儿 (P<0 .0 1 ) ,而 ET、NO水平则明显地高于正常儿童 (P<0 .0 1 )。结论 血清 SOD、ET、NO参与了支气管哮喘的发病过程 ,与发病机理有密切关系
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| 关 键 词： | 支气管哮喘 超歧过氧化物酶 内皮素 一氧化氮 儿童 |
| 文章编号： | 1008-7044(2004)06-0457-02 |
| 修稿时间： | 2004年5月12日 |
Clinical significance of serum SOD,ET and NO levels in children with bronchial asthma |
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| GAO Chang-long..Clinical significance of serum SOD,ET and NO levels in children with bronchial asthma[J].Journal of Huaihai Medicine,2004,22(6):457-458. |
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| Authors: | GAO Chang-long |
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| Abstract: | Objective To study the changes of serum super-oxidate dismatase(SOD),endothelal(ET) and nitric oxide(NO) levels in children with bronchial asthma.Methods Serum SOD and ET levels were determined by RIA,and NO level by chemistry in 36 children with bronchial asthma and 35 normal controls.Results Serum ET and NO levels in bronchial asthma children were significantly higher than those in normal controls( P <0.01),while SOD level decreased( P <0.01).Conclusion Serum ET,NO and SOD might play an important role in bronchial asthma children recovery and be closely related to the mechanism of bronchial asthma children. |
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| Keywords: | Bronchial asthma Superoxide dismatase(SOD) Endothelal(ET) Nitric oxide(NO) Child |
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