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| Mixed Medullary-follicular Thyroid Carcinoma： Report of a Case and Review of the Literarture | |
| 引用本文： | Xiangtao Ma Liwei Yu Jing Fu Shan Wang Ruyu Du Zhirong Cui. Mixed Medullary-follicular Thyroid Carcinoma： Report of a Case and Review of the Literarture[J]. 中国肿瘤临床(英文版), 2005, 2(6): 907-909. DOI: 10.1007/BF02789664 |
| 作者姓名： | Xiangtao Ma Liwei Yu Jing Fu Shan Wang Ruyu Du Zhirong Cui |
| 作者单位： | [1]Department of Surgery, Beijing HaidianHospital, Beijing 100080, China. [2]Department of Pathology, Beijing Haidian Hospital, Beijing 100080, China. [3]Department of Surgery and Division ofSurgical Oncology, Peking UniversityPeople＇s Hospital, Beijing 100044,China. |
| 摘 要： | Mixed medullary-follicular carcinomas （MMFCs） are tumors of the thyroid that display morphological and immunohistochemical features of both medullary and follicular neoplasms. These tumors are rare and less than 40 cases have been described in the literature since the early 1980s The term medullary-follicular thyroid carcinoma denotes a tumor which exhibits the features of a medullary carcinoma and shows positive expression of calcitonin on immunohistochemistry. It is a follicular-derived thyroid carcinoma and is positive for thyroglobulin expression within the same tumor. Most reported cases have lymph node involvement at the time of diagnosis. In cases having disease progression, distant metastases develop in the lung, liver, mediastinum and bone. We report a case of a male patient with mixed medullary-follicular thyroid carcinoma and a review of the literature. |
| 关 键 词： | 脊椎滤泡 甲状腺癌 病理学 免疫组织化学 |
| 收稿时间： | 2005-09-16 |
| 修稿时间： | 2005-09-30 |
Mixed medullary-follicular thyroid carcinoma: Report of a case and review of the literature |
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| Xiangtao Ma,Liwei Yu,Jing Fu,Shan Wang,Ruyu Du,Zhirong Cui. Mixed medullary-follicular thyroid carcinoma: Report of a case and review of the literature[J]. Chinese Journal of Clinical Oncology, 2005, 2(6): 907-909. DOI: 10.1007/BF02789664 | |
| Authors: | Xiangtao Ma Liwei Yu Jing Fu Shan Wang Ruyu Du Zhirong Cui |
| Affiliation: | 1. Department of Surgery, Beijing Haidian Hospital, Beijing 100080, China 2. Department of Pathology, Beijing Haidian Hospital, Beijing 100080, China 3. Department of Surgery and Division of Surgical Oncology, Peking University People's Hospital, Beijing 100044,China |
| Abstract: | Mixed medullary-follicular carcinomas (MMFCs) are tumors of the thyroid that display morphological and immunohistochemical features of both medullary and follicular neoplasms. These tumors are rare and less than 40 cases have been described in the literature since the early 1980s.[1] The term medullary-follicular thyroid carcinoma denotes a tumor which exhibits the features of a medullary carcinoma and shows positive expression of calcitonin on immunohistochemistry. |
| Keywords: | mixed medullary-follicular thyroid carcinoma calcitonin thyroglobulin. |
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