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Predictors of poor pre-operative psychological status among patients with cartilage defects
Institution:1. Department of Orthopaedics, Ohio State University Wexner Medical Center, Columbus, OH, United States;2. Department of Orthopaedics, Sports Medicine, Ohio State University, Wexner Medical Center, United States;3. The Ohio State University College of Medicine, Ohio State University, Wexner Medical Center, United States;4. Sports Medicine, Cleveland Clinic Foundation, United States;5. Department of Psychology, Ohio State University, Columbus, OH, United States;6. Division of Physical Therapy, School of Health and Rehabilitation Sciences, Ohio State University and Jameson Crane Sports Medicine Research Institute, Ohio State University, United States;7. Cartilage Restoration Program, Ohio State University, Wexner Medical Center, United States;1. Anatomy Laboratory, Faculty of Medicine, University of Thessaly, Larissa, Greece;2. Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Thessalia, Larissa, Greece;3. Laboratory of Mechanics and Strength of Materials, Department of Mechanical Engineering, University of Thessaly Volos, Volos, Greece;4. Complex Joint Reconstruction Center, Hospital for Special Surgery, New York, NY, USA;1. Dept. of Orthopaedics, University of North Carolina, Chapel Hill, NC, United States;2. School of Osteopathic Medicine, Campbell University, Lillington, NC, United States;1. Graduate School of Health Sciences, Morinomiya University of Medical Sciences, Osaka, Japan;2. Department of rehabilition, Yamamuro Clinic, Toyama, Japan;3. Musculoskeletal Intervention Center, Okuno Clinic, Tokyo, Japan;4. Inclusive Medical Science Research Institute, Morinomiya University of Medical Sciences, Osaka, Japan;5. AR-Ex medical research center, Tokyo, Japan;2. Department of Orthopedic Surgery, Chaim Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Derech Sheba 2, Ramat Gan, Israel;3. Montefiore Medical Center, 1250 Waters Place 11th Floor, Bronx, NY 10461, United States;4. Sports Medicine Institute, Hospital for Special Surgery, 535 E 70th St, New York, NY 10021, United States;1. Department of Sports Medicine, Peking University Third Hospital, Beijing, China;2. Institute of Sports Medicine of Peking University, Beijing, China;3. Beijing Key Laboratory of Sports Injuries, Beijing, China;4. Peking University Health Science Center, Beijing, China
Abstract:BackgroundWe evaluated the risk factors for pain catastrophizing, kinesiophobia, and elevated depressive symptoms among patients undergoing high-grade cartilage defect surgery. We hypothesized that cartilage patients would demonstrate high scores on pain catastrophizing, kinesiophobia, and depression testing prior to surgery.MethodsTwo hundred and ten patients undergoing surgery for high-grade cartilage defects (56% chondroplasty, 36% microfracture, 22% autologous chondrocyte implantation) completed a preoperative survey before undergoing surgery. Outcome scores assessed were: International Knee Documentation Committee-Symptom (IKDC-S) score, Tegner activity score, Pain catastrophizing scale (PCS), Tampa scale for kinesiophobia (TSK-11), and Patient Health Questionnaire depression scale (PHQ-9). Multivariate logistic regression was used to determine what pre-operative factors predicted pain catastrophizing, kinesiophobia, and elevated depressive symptoms.ResultsThe mean pre-operative Tegner score was 5.8 (SD 2.4) and IKDC-S score was 44.7 (SD 11.1). Prior to surgery, 19% had abnormal pain catastrophizing (PCS ≥ 20 points), 14.4% had moderate-severe depression (PHQ ≥ 10), and 49.0% had high kinesiophobia (TSK-11 ≥ 25). Lower pre-operative Tegner scores predicted moderate-severe depressive symptoms (per point decrease, OR 1.36, 95% CI 1.06, 1.76; p = 0.008). Predictors of elevated pain catastrophizing were lower pre-operative IKDC-S scores (per 5-point decrease, OR 1.28, 95% CI 1.08, 1.51; p = 0.002) and symptom duration >6 months (OR 2.20 CI 1.14, 4.32; p = 0.02). A lower pre-operative IKDC-S score (per 5-point decrease, OR 1.17, CI 1.03, 1.33; p = 0.02) predicted elevated kinesiophobia.ConclusionLow self-reported function, low activity level and symptom duration greater than six months are associated with poor preoperative psychological status.
Keywords:Psychological status  Cartilage defects  Chondral injury  Kinesiophobia  Pain catastrophizing
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