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Nanoparticle theranostics in cardiovascular inflammation
Affiliation:1. Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom;2. Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy;3. Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom;4. Department of Internal Medicine, Jagiellonian University, Collegium Medicum, Kraków, Poland;5. Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy
Abstract:Theranostics, literally derived from the combination of the words diagnostics and therapy, is an emerging field of clinical and preclinical research, where contrast agents, drugs and diagnostic techniques are combined to simultaneously diagnose and treat pathologies. Nanoparticles are extensively employed in theranostics due to their potential to target specific organs and their multifunctional capacity. In this review, we will discuss the current state of theranostic nanomedicine, providing key examples of its application in the imaging and treatment of cardiovascular inflammation.
Keywords:Atherosclerosis  Cardiovascular disease  Inflammation  Myocardial infarction  Nanoparticles  Theranostics
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