| Institution: | 1. Wrightington, Wigan and Leigh NHS Foundation Trust, UK;2. Royal Gwent Hospital Newport, UK;3. Rama Medical College and Hospital, Kanpur, India;1. Department of Orthopaedic Surgery, Rutgers University, New Jersey Medical School, 140 Bergen Street, D-1610, Newark, NJ, 07103, USA;2. Department of Surgery, Rutgers University, New Jersey Medical School, 140 Bergen Street, D-1610, Newark, NJ, 07103, USA;3. Rutgers New Jersey Medical School, USA;1. Ghaem Clinical Research Development Unit, Guilan University of Medical Sciences, Rasht, Iran;2. Statistics Department, School of Health, Guilan University of Medical Sciences, Rasht, Iran;3. Department of Anatomical Sciences & Cell Biology, Mashhad University of Medical Sciences, Mashhad, Iran;1. Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, 110029, India;2. Nepal Cancer Hospital and Research Center, Lalitpur, Nepal |
| Abstract: | BackgroundLong-term outcome of Total Hip arthroplasty (THA) in Ankylosing Spondylitis (AS) remains unreported. Literature suggests a higher overall failure rate in ankylosing spondylitis as compared to osteoarthritis. Concern has been expressed regarding joint survival, given that recipients are generally young. The results of cemented THA in patients with ankylosing spondylitis were studied to determine the utility of THA for these patients.MethodsConsecutive series of 96 patients (77 males (80%) and 19 females (20%)) with ankylosing spondylitis who underwent 154 cemented THAs at a tertiary referral orthopaedic centre between January 1990–September 2015 were retrospectively analyzed for clinical and radiological outcomes; 58 patients (60.4%) underwent bilateral surgery.ResultsMean age at surgery was 48 years. Average follow up was 12.8 (2.1–24.8) years. 95% of the patients had a good or excellent post-operative outcome.Out of the total 154 hips operated on, 11% (17 hips) developed post-operative complications. Overall, 15 hips (9.7%) required a revision of the procedure, with the most common indication being aseptic loosening of the acetabulum. Average time to revision was 8.5 years (2–15). Survivorship analysis revealed probability of survival of both components at the end of 10 years, with revision due to any reason as the end point to be 92% (with 95% confidence intervals).21 hips (14%) developed heterotopic ossification post-operatively, of which 4 patients (2%) had clinically significant ossification (Brooker III or IV).ConclusionThis is one of the largest series of patients with ankylosing spondylitis with long term follow up available. Cemented THA in patients with ankylosing spondylitis provided consistently good and predictable long term results, with low rate of complications and revisions. |
