n-BCA胶在介入治疗创伤性颈动脉海绵窦瘘中的应用

目的 探讨应用n-BCA胶介入栓塞创伤性颈动脉海绵窦的方法和安全性.方法 回顾性分析应用液体胶介入栓塞治疗的11例创伤性颈动脉海绵窦瘘的患者,包括临床特点、治疗方法和疗效.结果 本组11例患者中,因球囊移位或渗漏导致的栓塞术后复发3例;球囊或弹簧圈栓塞后瘘口残留4例;瘘口太小球囊无法进入海绵窦内3例;因碎骨片反复刺破球囊1例.栓塞所使用的n-BCA胶的浓度从25%～50%,其中4例在注胶过程中使用不可脱球囊经颈内动脉暂时封闭瘘口,7例没有采用保护措施.4例采用保护性球囊的患者中均无n-BCA粘住球囊或微导管,所有11例患者均无n-BCA胶返流入颈内动脉的现象,术后即刻造影均提示瘘口完全消失.1例患者术后出现患侧玻璃体出血,经手术清除积血后视力恢复;1例术后出现患侧外展神经麻痹,半年后自行恢复;1例伴有外伤性视神经损伤,术后视力未恢复,无其他介入相关并发症.临床随访3个月-5年,所有患者均无临床症状复发,均恢复正常生活.结论 单独采用n-BCA胶或联合球囊或弹簧圈介入栓塞创伤性颈动脉海绵窦瘘是安全、有效的方法.

Abstract：

Objective To explore the method and safety of endovascular treatment of traumatic direct carotid cavernous fistulas with n - Butyl - 2 - Cyanoacrylate. Method A total of 11 patients with traumatic direct carotid cavernous fistulas treated by endovascular embolization with n - Butyl -2 - Cyanoacrylate( n - BCA ) were retrospectively analyzed, including the clinical presentations, methods of treatment and results of follow - up. Results In the 11 patients treated with n - BCA embolization, 3 with recurrent fistula because of premature balloon deflation or migration,4 with residual fistula after the balloons or microcoils detached, 3 unable to guide balloon into the small fistulous orifice and 1 repeated puncture of the detachable balloon by the bony fragment. The concentration of n - BCA ranged from 25% to 50%,protective balloon was used in 4 cases and there was no adhesion fo the n - BCA to the protective balloon or the microcatheter or n - BCA reflux into the parent arteries. Complete angiographic obliteration was documented in all patients right after the embolization. There was no permanent procedure - related morbidity. Clinical cure was achieved in all case and the clinical follow - up period ranged from 3 months to 5 years, all the patients restored to their normal life. Conclusions Endovascular embolization with n - BCA is a safe,efficient method for the treatment of traumatic direct carotid cavernous fistulas when angiographic cure and parent artery preservation are not achieved by detachable balloon embolization.

Endovascular treatment of traumatic direct carotid cavernous fistulas with n-Butyl-2-Cyanoacrylate

Objective To explore the method and safety of endovascular treatment of traumatic direct carotid cavernous fistulas with n - Butyl - 2 - Cyanoacrylate. Method A total of 11 patients with traumatic direct carotid cavernous fistulas treated by endovascular embolization with n - Butyl -2 - Cyanoacrylate( n - BCA ) were retrospectively analyzed, including the clinical presentations, methods of treatment and results of follow - up. Results In the 11 patients treated with n - BCA embolization, 3 with recurrent fistula because of premature balloon deflation or migration,4 with residual fistula after the balloons or microcoils detached, 3 unable to guide balloon into the small fistulous orifice and 1 repeated puncture of the detachable balloon by the bony fragment. The concentration of n - BCA ranged from 25% to 50%,protective balloon was used in 4 cases and there was no adhesion fo the n - BCA to the protective balloon or the microcatheter or n - BCA reflux into the parent arteries. Complete angiographic obliteration was documented in all patients right after the embolization. There was no permanent procedure - related morbidity. Clinical cure was achieved in all case and the clinical follow - up period ranged from 3 months to 5 years, all the patients restored to their normal life. Conclusions Endovascular embolization with n - BCA is a safe,efficient method for the treatment of traumatic direct carotid cavernous fistulas when angiographic cure and parent artery preservation are not achieved by detachable balloon embolization.