| 2型糖尿病患者颈动脉粥样硬化与总胆红素的关系 |
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| 引用本文： | 徐曜,刘涛,明洁,王尧,翟文松,姬秋和. 2型糖尿病患者颈动脉粥样硬化与总胆红素的关系[J]. 中华全科医师杂志, 2011, 10(3): 209-211. DOI: 10.3760/cma.j.issn.1671-7368.2011.03.025 |
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| 作者姓名： | 徐曜 刘涛 明洁 王尧 翟文松 姬秋和 |
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| 作者单位： | 1. 四川省西昌解放军第五一九医院内科,615000
2. 解放军第四军医大学西京医院内分泌代谢科,西安,710032 |
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| 摘 要： | 对548例2型糖尿病患者行颈动脉超声检查,比较分析有、无颈动脉粥样硬化患者的血糖、糖化血红蛋白、胆红素、血脂等指标差异.有、无动脉粥样硬化患者的血清胆红素水平分别为（13.0±7.1）和（10.9±4.9）μmol/L,两者之间差异有统计学意义（P＜0.01）;logistic回归分析显示总胆红素水平与颈动脉粥样硬化呈负相关（P＜0.05）.提示高血清胆红素可能对2型糖尿病大血管病变具有保护作用.
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| 关 键 词： | 糖尿病 2型 颈动脉疾病 |
Relationship between total sermn bilirubin and carotid atherosclerosis in type 2 diabetes mellitus |
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| XU Yao,LIU Tao,MING Jie,WANG Yao,ZHAI Wen-song,JI Qiu-he. Relationship between total sermn bilirubin and carotid atherosclerosis in type 2 diabetes mellitus[J]. Chinese JOurnal of General Practitioners, 2011, 10(3): 209-211. DOI: 10.3760/cma.j.issn.1671-7368.2011.03.025 |
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| Authors: | XU Yao LIU Tao MING Jie WANG Yao ZHAI Wen-song JI Qiu-he |
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| Affiliation: | . Department of Endocrinology and Metabolism, Xijing Hospital, Xi＇an 710032 ,China |
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| Abstract: | Ultrasonography examinations were performed for carotid atherosclerosis in 548 patients with type 2 diabetes mellitus (T2DM). Blood glucose, glycosylated hemoglobin, total serum bilirubin, uric acid, total cholesterol ( TC ), triglycerides ( TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL) were measured. Total serum bilirubin level in T2DM patients without carotid atherosclerosis was (13.0±7. 1 )μmol/L, while that was (10. 9 ± 4. 9 )μmol/L in patients with carotid atherosclerosis (P ＜0. 01 ). The logistic analysis showed that total serum bilirubin level was negatively related to the presence of carotid atherosclerosis ( P ＜ 0. 05 ), which indicated that higher level of total serum bilirubin might be a protective factor for macroangiopathy in T2DM. |
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| Keywords: | Diabetes mellitus,type 2 Carotid artery diseases |
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