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神经内镜下经鼻蝶窦垂体腺瘤切除术并发症的防治
引用本文:郑勇,吴永刚,王继超,阿不都克尤木,杨小朋. 神经内镜下经鼻蝶窦垂体腺瘤切除术并发症的防治[J]. 中华神经外科杂志, 2011, 27(3). DOI: 10.3760/cma.j.issn.1001-2346.2011.03.004
作者姓名:郑勇  吴永刚  王继超  阿不都克尤木  杨小朋
作者单位:新疆维吾尔自治区人民医院神经外科,乌鲁木齐,830001
基金项目:吴阶平医学基金会临床科研专项资助基金
摘    要:目的 探讨神经内镜下经单鼻孔蝶窦切除垂体腺瘤的并发症的防治.方法 对在神经内镜下经单鼻孔蝶窦切除垂体腺瘤253例临床资料分析.结果 肿瘤全切除216例(85.38%),次全切除26例(10.28%),部分切除11例(4.34%),无手术死亡病例.术后并发暂时性尿崩45例,术后垂体功能低下9例,脑脊液鼻漏2例,鼻腔黏膜出血2例,嗅觉丧失2例,无发生颈内动脉、视神经损伤,无蛛网膜下腔出血、颅内和局部感染,无鼻中隔穿孔.结论 神经内镜下经单鼻孔蝶窦垂体腺瘤切除术手术创伤小,术前做好评估,术中精细操作,术后并发症可减至最小,是一种安全、有效的治疗方法.
Abstract:
Objective To discuss the complicatiaons's prophylaxis of removing pituitary adenomas of neuroendoscopy in tranasphenoidal surgery. Method To analayze 253 cases Clinically date of pituitary adenoma were treated by endoscopic endonasal transsphenoidal surgery. Results The tumor removal was total in 216 ( 85.38% ) cases, subtotal in 26 ( 10. 28% ), and partial in 11 ( 4. 34% ). Temporary diabetes insipidus in 45 cases, pituitary function subnomorlity in 9 cases, cerebrospinal fluid leaks in 2 cases, nostril stenoses in 2 cases, anodmia in 2 cases, there were no internal carotid artery and optic nerve lesion, no subarachnoid hemorrhage and intracranial infection, no nasoseptal tresis. Conclusions Featured by minimal invasion and less postoperative complications, neurendoscopic endonasal transsphenoidal surgery is a safe and effective method for the treatment of pituitary adenoma.

关 键 词:垂体肿瘤  内镜  经鼻蝶窦手术  并发症

Complications's prophylaxis in neuroendoscopic endonasal transsphenoidal surgery for pituitary adenomas
ZHENG Yong,WU Yong-gang,WANG Ji-chao,ABUDUKE You-mu,YANG Xiao-peng. Complications's prophylaxis in neuroendoscopic endonasal transsphenoidal surgery for pituitary adenomas[J]. Chinese Journal of Neurosurgery, 2011, 27(3). DOI: 10.3760/cma.j.issn.1001-2346.2011.03.004
Authors:ZHENG Yong  WU Yong-gang  WANG Ji-chao  ABUDUKE You-mu  YANG Xiao-peng
Abstract:Objective To discuss the complicatiaons's prophylaxis of removing pituitary adenomas of neuroendoscopy in tranasphenoidal surgery. Method To analayze 253 cases Clinically date of pituitary adenoma were treated by endoscopic endonasal transsphenoidal surgery. Results The tumor removal was total in 216 ( 85.38% ) cases, subtotal in 26 ( 10. 28% ), and partial in 11 ( 4. 34% ). Temporary diabetes insipidus in 45 cases, pituitary function subnomorlity in 9 cases, cerebrospinal fluid leaks in 2 cases, nostril stenoses in 2 cases, anodmia in 2 cases, there were no internal carotid artery and optic nerve lesion, no subarachnoid hemorrhage and intracranial infection, no nasoseptal tresis. Conclusions Featured by minimal invasion and less postoperative complications, neurendoscopic endonasal transsphenoidal surgery is a safe and effective method for the treatment of pituitary adenoma.
Keywords:Pituitary neoplasms  Endoscopes  Transsphenoidal surgery  Complication
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