| 短暂性脑缺血发作患者纤溶功能研究 |
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| 引用本文： | 杨春祥,周翠萍,毕晓霞. 短暂性脑缺血发作患者纤溶功能研究[J]. 北京医学, 2002, 24(4): 242-243. DOI: 10.3969/j.issn.0253-9713.2002.04.008 |
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| 作者姓名： | 杨春祥 周翠萍 毕晓霞 |
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| 作者单位： | 北京市酒仙桥医院,100016 |
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| 摘 要： | 目的研究短暂性脑缺血发作(TIA)患者血浆纤溶功能的变化.方法对22例颈内动脉系统TIA患者血浆组织型纤溶酶原激活物(t-PA)及其快速抑制物(PAI)的活性、D-二聚体(D-D)及纤维蛋白原(FbG)含量进行检测,并与对照组进行比较.结果 TIA组血浆t-PA活性明显低于对照组(P<0.05),而PAI活性和D-D及FbG含量则明显高于对照组(P<0.05).结论 TIA患者存在血浆纤溶功能异常,可能为TIA反复发作的一个重要因素.
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| 关 键 词： | 短暂性脑缺血发作 纤溶功能 |
Study of fibrinolytic function in the patients with transient ischemic attack |
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| Yang Chunxiang,Zhou Cuiping,Bi Xiaoxia. Study of fibrinolytic function in the patients with transient ischemic attack[J]. Beijing Medical Journal, 2002, 24(4): 242-243. DOI: 10.3969/j.issn.0253-9713.2002.04.008 |
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| Authors: | Yang Chunxiang Zhou Cuiping Bi Xiaoxia |
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| Abstract: | Objective To study the alteration of plasma fibrinolytic function in patients with transient ischemic attack(TIA).Methods Activities of tissue type plasminogen activator(t PA) and plasminogen activator inhibitor(PAI) and contents of D dimeter(D D) and fibrinogen(FbG) were determined in 22 patients with TIA and compared with 22 normal controls.Results Plasma t PA activity level in TIA group was significantly lower than that in control group ( P <0.05).But the levels of PAI,D D and FbG in TIA group were significantly higher than those in control group ( P <0.05). Conclusions Abnormal fibrinolytic function may be an important factor of TIA recurrence in TIA patients. |
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| Keywords: | Transient ischemic attack (TIA) Fibrinolytic function |
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