液基细胞学联合阴道镜检查在宫颈病变筛查中的临床应用

目的探讨液基细胞学(TCT)联合阴道镜检查对宫颈病变筛查的诊断价值。方法对1 138例受检者行液基细胞学检查,对其中195例细胞学阳性者行阴道镜及镜下多点活组织病理检查,诊断结果与病理组织学诊断对照。结果行TCT检查1 138例,细胞学阳性195例,占17.14%,其中不典型鳞状上皮细胞(ASCUS)157例(13.80%),低度鳞状上皮内病变(LSIL)28例(2.46%),高度鳞状上皮内病变(HSIL)10例(0.88%)。对所有细胞学阳性病例及临床高度可疑宫颈病变的患者均行阴道镜检查及镜下活组织病理检查。异常阴道镜图象139例(71.28%)。与病理组织学对照,ASCUS(CINI66例、CINⅡ1例)、LSIL(CINⅠ13例、CINⅡ2例、CINⅢ6例、SCC 1例);HSIL(CINⅡ3例、CINⅢ3例、SCC 4例)。结论应用TCT筛查子宫颈病变,细胞学阳性者联合阴道镜下活组织病理检查,能早期发现宫颈癌前病变,防治宫颈癌。

COMBINED COLPOSCOPY WITH LIQUID- BASED CYTOLOGY IN CERVICAL LESIONS SCREENING

Objective To determine the diagnosis value of liquid -based cytology（TCT） combined with colposcopy in cervical lesions screening. Methods 1 138 women received TCT,and 195 of them got colposcopy and autopsy, diagnosis results were compared with Histopathology. Results 195 out of 1138 （17.14%） TCT examinations were cytology positive, 157 cases （13.80%） were Atypical squamous cells （ASCUS）, 28 cases （2.46%） were low -grade squamous intraepithelial lesions （LSIL） and 10 cases （0.88%） were high -grade squamous intraepithelial lesions （HSIL）. All positive cases and clinical highly suspicious cytology cervical lesions patients underwent eolposcopy and endoscopic biopsy pathology. 139 cases （71.28%） had abnormal colposcopy images. And compared with histological, ASCUS （CINI66 cases, CIN II 1 case）, LSIL （CIN I 13 cases, CIN II 2 cases, CIN III 6 cases, SCC1 cases） ; HSIL （CIN II 3 cases, CIN III 3 cases, SCC4 cases）. Conclusion Cervical lesions screening by liquid -based cytology（TCT） ,with Biopsy pathology under colposcopy, Cervical lesions could be determined and prevented if cytology positive.