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子宫内膜癌组织中骨桥蛋白的表达及意义
引用本文:李艳霞. 子宫内膜癌组织中骨桥蛋白的表达及意义[J]. 中国现代医生, 2010, 48(6): 30-31
作者姓名:李艳霞
作者单位:山西运城临猗妇幼保健院,山西,运城,044100
摘    要:目的检测子宫内膜癌组织中骨桥蛋白(0PN)的表达,探讨其与子宫内膜癌发生、发展及临床病理特征的关系。方法采用免疫组化法对68例手术切除的子宫内膜癌患者存档石蜡标本进行OPN检测,分析其表达水平。结果子宫内膜癌组织中OPN表达与患者细胞分化程度、临床分期及淋巴结转移有密切关系(P〈0.05)。结论OPN的表达随肿瘤恶性程度的增高而增强,可能成为判断子宫内膜癌预后的指标。

关 键 词:骨桥蛋白  子宫内膜癌  免疫组化

Osteopontin Expression in Endometrial Carcinoma:Clinical Significance
LI Yanxia. Osteopontin Expression in Endometrial Carcinoma:Clinical Significance[J]. , 2010, 48(6): 30-31
Authors:LI Yanxia
Affiliation:LI Yanxia Linyi Maternal , Child Healthcare Hospital,Yuncheng 044100,China
Abstract:Objective To investigate the expression of osteopontin in endometrial carcinoma and its relationship with the occurrence,development and clinical pathological characteristics of endometrial carcinoma.Methods Osteopontin was detected in 68 patients with endometrial cancer by immunohistochemical method.Results Osteopontin expression was related to the cell differentiation,clinical staging and lymph node metastasis in endometrial carcinoma.Conclusion Osteopontin expression is increased with the degree of malig...
Keywords:Osteopontin  Endometrial carcinoma  Immunohistochemistry  
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