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针刺干预大鼠实验性脑梗塞的形态学研究——Ⅰ软脑模动脉网的代偿及动态定量观察
引用本文:翟娜,杜元灏,石学敏,许屏. 针刺干预大鼠实验性脑梗塞的形态学研究——Ⅰ软脑模动脉网的代偿及动态定量观察[J]. 针刺研究, 1993, 0(1)
作者姓名:翟娜  杜元灏  石学敏  许屏
作者单位:天津中医学院第一附属医院,天津中医学院第一附属医院,天津中医学院第一附属医院,天津第二医学院组胚 300193,300193,300193
摘    要:以脑灌注方法动态观察了阻断大鼠一侧大脑中动脉(MCA_0)所致大脑表面缺血区内软脑膜动脉网的代偿及针刺效应。MCA_0阻断后立即灌注,整个阻断侧大脑半球为空白的缺血区;阻断 MCA_03小时后,针刺组缺血区边缘末梢吻合网的血流已部分涌入缺血区,并随时间延长,缺血区内充盈血管逐渐增多,而非针刺组仅可见到缺血区内有个别的代偿血管。实验提示:阻断 MCA_0初期,MCA 血管系统存在较严重的血管痉挛,故旁侧动脉的代偿基本不能实现,针刺则在缺血早期快速缓解了血管痉挛,使之接受代偿血流。

关 键 词:脑灌注  大脑中动脉  脑梗塞  软脑膜动脉网  针刺

MORPHOLOGICAL STUDY ON ACUPUNCTURE IN INTERFERING EXPERIMENTAL CEREBRAL INFARCTION IN RAT——Ⅰ.Compensation of Cerebal PIA Mater Artery in Cerebral Surface
Abstract:Occluding unilateral middle cerebrarl artery (MCAo) of rat,the compensatoryblood vessels (CBV) within ischemic area in cerebral surface shown by cerebralperfusion and effect of acupuncture were observed dynamically.Perfusing im-mediately after MCAo,there was no any blood vessel in the ischemic area.Inacupuncture group,the CBV had extended a lot from anastomotic network ofcerebral pin mater (ACA-MCA,PCA-MCA) located in marginal zone of ischemicarea 3 hs after MCAo.6,24 and 48 hs after MCAo,the CBV increased muchmore than control group (non-acupuncture) P<0.01.The experiment pointed outthat there existed a serious vasospasm in the MCA system in initial stage ofMCAo,which led up to decompensation in the ischemic area.The acupuncturecan remit the vasospasm,and reverse the deteriorated process in early.
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