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益生菌联合西替利嗪治疗儿童慢性荨麻疹疗效观察
引用本文:刘金花,李庆祥,陈俊钊,黄文富,曾美,王翠彦,何伟锋.益生菌联合西替利嗪治疗儿童慢性荨麻疹疗效观察[J].中国热带医学,2013,13(4):504-505.
作者姓名:刘金花  李庆祥  陈俊钊  黄文富  曾美  王翠彦  何伟锋
作者单位:1. 惠州市中心人民医院皮肤科,广东惠州,516001
2. 惠州市第一人民医院消化内科,广东惠州,516003
基金项目:惠州市科技计划项目(项目编号:2012Y109)
摘    要:目的:探讨益生菌—思连康联合盐酸西替利嗪对慢性荨麻疹患儿疗效和安全性。方法:66例慢性荨麻疹患儿随机进入观察组和对照组:观察组,34例,盐酸西替利嗪滴剂,1mL,口服,1次/d;同时加用思连康片1g,3次/d,共14d;对照组,32例,盐酸西替利嗪滴剂,1mL,口服,1次/d,共14d。治疗2周后进行疗效评价。结果:观察组有效率88.2%,对照组有效率62.5%,两组比较差异有统计学意义(P〈0.05);且均无明显不良反应。结论思连康联合西替利嗪治疗儿童慢性荨麻疹短期疗效较高,安全性高。

关 键 词:思连康  益生菌  西替利嗪  慢性荨麻疹  儿童

Therapeutic effect of probiotics combined with cetirizine on chronic urticaria in children
Institution:LIU Jin-hua,LI Qing-xiang,Chen Jun-zhao,et al.(1Dermatological Department of Huizhou Municipal Central Hospital,Huizhou 51600,Guangdong,P.R..China)
Abstract:Objective To explore curative effect and safety of Siliankang combined with cetirizine hydrochloride on child chronic urticaria patients. Methods The 66 children with chronic urticaria were randomly divided into observation group(34 cases)treated with cetirizine hydrochloride drops,1mL,P.O,Qd;at the same time combined with Si Lian Kang 1g,P.O,Tid,total of 14 days and control group(32 cases) treated with only with cetirizine hydrochloride drops,1mL,P.O,Qd,for a course of 14 days.The results in both groups were evaluated two week later. Results The effective rate was 88.2% in the observation group and 62.5% in the control group,showing significant difference between two groups(P0.05).And there were no obvious adverse reactions in the observation group. Conclusion Short-term curative effect of Shiliankang combined with cetirizine is safe and highly effective on child chronic urticaria.
Keywords:Shiliankang  Probiotics  Cetirizine  Chronic urticaria  Children
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