卒中后抑郁的长程脑电图研究

目的 探讨卒中后抑郁患者长程脑电图的特点。方法 选取卒中后抑郁患者101例，行长程脑电图，计算睁闭眼实验后第一个10 sec内脑电图δ、θ、α、β波的时间，以及整夜S1、S2、S3、S4睡眠阶段和快动眼睡眠（rapid eye movement sleep，REM）占总睡眠时间的比例，与健康对照组脑电图结构进行比较。结果 卒中后抑郁组较对照组脑电图上慢波（δ和θ波）明显增加（δ波P＝0.001，θ波P＝0.005），α波明显减少（P＝0.008），β波无显著差异。和正常对照组睡眠结构比较，卒中后抑郁组睡眠S2、S3和S4阶段比例减少（P值分别为0.008、0.004），睡眠S1阶段和REM比例增加（P值分别为0.001和0.006）。结论 卒中后抑郁症患者脑电背景慢波增多；卒中后抑郁症患者浅睡眠多，而中到深度睡眠减少。

Investigation of the Long-time Electroencephalogram of the Patients with Post-stroke Depression

Objective To investigate the long-time electroencephalogram（EEG） characteristics of the patients with post-stroke depression（PSD）. Methods We collected 101 patients with PSD, and gave them the long-time EEG test, then calculated the time of the δ,θ,a, β wave in the first 10 s alter the Open-Closed eyes test and the proportion of the sleep stages S1, $2, $3, $4 and rapid eye movement（REM） in the all sleeping time. All these data were compared with the healthy control group＇s EEG structure. Results The slow wave（6 and 0 wave） increased significantly in PSD group than that in the control group（6 wave P-0.001, 0 wave P=0.005）, ct wave significantly reduced and β wave had no significant difference. Compared with the healthy control group, the proportion of the sleep stages S2,S3, S4 of PSD group were reduced（the P followed by 0.008, 0.004）. The proportion of the stage S1 and REM was increased （the P lbllowed by 0.001 and 0.006）. Conclusion The slow wave increased in the PSD patients＇ EEG. The light sleep increased, and the moderate-deep sleep reduced in the PSD patients.