生物羊膜移植联合小梁切除术用于青光眼再手术的疗效观察

目的:观察生物羊膜在青光眼再手术中应用的效果和安全性。方法:对31例(33眼)青光眼再手术病例施行小梁切除联合羊膜移植术,术后随访1a,检查记录术后视力、滤过泡、前房深度、眼压及术后并发症。结果:随访期间眼压由术前的(33.18±5.7)mmHg降至术后的(15.23±3.3)mmHg,比术前明显降低(P<0.05);术后1a眼压控制率为94%(31/33),保持功能性滤过泡27眼(82%);并发症主要为低眼压(6眼)和浅前房(4眼)。结论:生物羊膜移植联合小梁切除术可减少滤过道瘢痕形成,显著提高手术成功率,用于青光眼再手术安全有效。

Biological amnion transplantation combin-ed with trabeculectomy for re-operation of glaucoma

·AIM:To observe the effect and security of biological amnion used in the re-operation of glaucoma..METHODS:Trabeculectomy combined with biological amnion transplantation were performed in 31 cases(33 eyes)who underwent re-operation of glaucoma.After the operation patients were followed up for one year.The visual acuity,filtering blebs,anterior chamber depth,intraocular pressure(IOP)and complications were examined and recorded..RESULTS:During the period of follow-up,IOP fell from preoperative(33.18±5.7)mmHg down to postoperative(15.23±3.3)mmHg,and there was statistically significant difference(P<0.05).At one year after the operation,those whose IOP was controlled occupied 94%(31/33);27 eyes(82%)maintained functional filtering blebs.Main complications were ocular hypotension(6 eyes)and shallow anterior chamber(4 eyes)..CONCLUSION:Biological amnion transplantation com-bined with trabeculectomy can reduce scar formation,and improve the success rate remarkably.It is safe and effective to be used in the re-operation of glaucoma..