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Expression and prognostic significance of THBS1, Cyr61 and CTGF in esophageal squamous cell carcinoma
Authors:Zhu-Qing Zhou  Wei-Hua Cao  Jian-Jun Xie  Jing Lin  Zhong-Ying Shen  Qing-Ying Zhang  Jin-Hui Shen  Li-Yan Xu and En-Min Li
Institution:(1) Department of Biochemistry and Molecular Biology, Shantou University, Shantou, PR China;(2) Institute of Oncologic Pathology, Shantou University, Shantou, PR China;(3) Department of Hospice Care of the First Affiliated Hospital, Shantou University, Shantou, PR China;(4) Department of Public Health and Preventive Medicine, Medical College of Shantou University, Shantou, PR China;(5) Department of Clinical Pathology, Centre Hospital of Shantou City, 515041 Shantou, PR China
Abstract:

Background  

Thrombospondin1 (THBS1), cystene-rich protein 61 (Cyr61) and connective tissue growth factor (CTGF) are all involved in the transforming growth factor-beta (TGF-β) signal pathway, which plays an important role in the tumorigenesis. The purpose of this study is to explore the expression and prognostic significance of these proteins in esophageal squamous cell carcinoma (ESCC).
Keywords:
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