口腔颌面部非霍奇金淋巴瘤临床病理分析

目的:探讨与口腔颌面部非霍奇金淋巴瘤确诊相关的临床病理特点。方法:对2000-02—2012-03郑州大学附属洛阳市中心医院口腔颌面外科收治的17例非霍奇金淋巴瘤,进行回顾性临床病理分析。结果:口腔颌面部非霍奇金淋巴瘤可发生于任何年龄,男女之比为2.4∶1,可发生于颈部及颌下区、牙龈、腭部、腮腺、颊部及舌根部等。病理类型以B细胞淋巴瘤多见。临床及病理首诊确诊率均偏低。结论:口腔颌面部非霍奇金淋巴瘤临床表现多样,确诊依靠病理学诊断,但对取检标本及病理诊断均有较高要求,有些不典型病例需进行分子生物学检测及严密随访。

Clinicopathology of non-Hodgkin's Lymphoma in Oral and Maxillofacial Region

Objective: To summarize the clinical pathology and definite diagnosis of non-Hodgkin′s lymphoma(NHL) in oral and head region.Methods:17 cases with NHL admitted in Luoyang Central Hospital during 2000-02 to 2012-03 were retrospectively reviewed.Results: The patients with NHL have a wide range of age.Males are more than females,the ratio is 2.29∶1.The lesion located in cervical part,submaxillary region,gum,hard or soft palate,parotid gland,buccal area, and the base of tongue.The pathological diagnosis were mainly B cell lymphoma.The definite diagnosis rate was low during first visit.Conclusion: Clinical manifestations of oral-maxillofacial of non-Hodgkin′s lymphomas varied differently, higher requirements are needed in biopsy and pathology examination.Molecular biological detection and close follow-up study is needed in some atypical cases.