经导管动脉化疗栓塞术治疗原发性肝癌破裂大出血

目的探讨TACE治疗原发性肝癌破裂大出血的效果。方法回顾性分析21例接受TACE的原发性肝癌破裂大出血患者,对其TACE后出血改善情况、中远期生存率及其影响因素进行分析。结果 21例患者止血成功率为100%,术后平均动脉压由术前的（72.74±18.20）mmHg上升至（92.40±17.89）mmHg,与术前比较差异有统计学意义（P=0.0011）。术后3、6、12、24个月生存率分别为85.71%（18/21）、71.43%（15/21）、61.90%（13/21）、19.05%（4/21）。结论 TACE是治疗原发性肝癌破裂大出血的首选有效方法,患者预后受肝硬化程度、肝功能分级、肿瘤范围等因素影响。

Transcatheter arterial chemoembolization for massive hemorrhage due to primary liver cancer rupture

Objective To assess the effect of TACE for massive hemorrhage due to primary liver cancer (PLC) rupture. Methods Twenty-one patients with massive hemorrhage due to PLC rupture underwent TACE, and the hemostasis rate after TACE, outcomes and factors influencing median and long term survival were retrospectively analyzed. Results The hemostasis rate was 100%. The mean arterial pressure elevated from (72.74±18.20)mmHg to (92.40±17.89)mmHg after TACE (P=0.0011). The survival rate was 85.71% (18/21) at 3 months, 71.43% (15/21) at 6 months, 61.90% (13/21) at 12 months and 19.05% (4/21) at 24 months. Conclusion TACE is the first choice in treatment of PLC rupture, and the prognosis is associated with variable factors such as degree of liver cirrhosis, grade of liver function and extent of tumor, etc.