| 肝硬化患者血清sP-选择素与肝功能及肝纤维化的关系 |
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| 引用本文： | 刘展,周会新,王双喜.肝硬化患者血清sP-选择素与肝功能及肝纤维化的关系[J].医学临床研究,2008,25(2):199-200. |
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| 作者姓名： | 刘展 周会新 王双喜 |
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| 作者单位： | 1. 湖南省人民医院消化内科,湖南,长沙,410002
2. 中南大学药学院,湖南,长沙,410078 |
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| 摘 要： | 目的]探讨肝硬化患者血清可溶性粘附分子P-选择素(sP-选择素)与肝功能及肝纤维化的关系.方法]选择75例肝硬化患者,测定sP-选择素、肝功能及Ⅳ型胶原水平.结果]肝硬化组血清sP-选择素及Ⅳ型胶原水平均显著高于正常对照组;血清sP-选择素与肝功能、肝功能Child分级和Ⅳ型胶原水平明显相关.结论]血清sP-选择素水平可能是临床观察肝硬化患者病变活动的重要指标.
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| 关 键 词： | 肝硬化/血液 P选择素/血液 |
| 文章编号： | 1671-7171（2008）02-0199-02 |
| 收稿时间： | 2007-01-26 |
| 修稿时间： | 2007年1月26日 |
Relationship of Serum sP-selectin, Liver Function and Fibrosis in Patients with Hepatic Cirrhosis |
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| LIU Zhan,ZHOU Hui-xin,WANG Shuang-xi.Relationship of Serum sP-selectin, Liver Function and Fibrosis in Patients with Hepatic Cirrhosis[J].Journal of Clinical Research,2008,25(2):199-200. |
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| Authors: | LIU Zhan ZHOU Hui-xin WANG Shuang-xi |
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| Abstract: | Objective]To study the relationship of serum sP-selectin, liver function and fibrosis in patients with hepatic cirrhosis. Methods] Serum sP-selectin, liver function, and IV collagen in 75 patients with hepatic cirrhosis were detected. Results]The levels of serum sP-selectin and IV collagen in patients with hepatic cirrhosis were higher than those in normal control group. The level of serum sP-selectin was significantly related to liver function and fibrosis in patients with hepatic cirrhosis. Conclusion]The level of serum sP-selectin may be a indication of liver function and fibrosis in patients with hepatic cirrhosis. |
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| Keywords: | liver cirrhosis/BL P-selectin/BL |
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