Relative carriage rates of nuclear dehydrogenating clostridia in two populations of different colorectal cancer risk |
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| Authors: | SP Borriello BS Drasar A Tomkins and MJ Hill |
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| Institution: | .Bacterial Metabolism Research Laboratories, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire;* London School of Hygiene and Tropical Medicine, London WC1 |
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| Abstract: | Carriage of nuclear dehydrogenating clostridia has been associated with colon cancer and implicated in its aetiology. This study has compared the carriage of these organisms in a British population at high risk for the development of colon cancer with a low risk Nigerian population. Clostridia were found in all of the stools from both populations. Nuclear dehydrogenating clostridia were only found in the stools of the British subjects (32%). These results support the suggestion that the carriage rate of nuclear dehydrogenating clostridia in a population is related to the risk of colon cancer. |
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