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托吡酯片与丙戊酸钠缓释片治疗儿童癫痫的最小成本分析
引用本文:哈力,胡宝荣,侯振华. 托吡酯片与丙戊酸钠缓释片治疗儿童癫痫的最小成本分析[J]. 中国药房, 2005, 16(21): 1633-1634
作者姓名:哈力  胡宝荣  侯振华
作者单位:哈尔滨医科大学第一临床医学院药剂部,哈尔滨市,150001
摘    要:目的:探讨2种药物治疗儿童癫痫的成本和效果。方法:72例癫痫患儿分别应用托吡酯片与丙戊酸钠缓释片,观察疗效, 并运用药物经济学原理进行最小成本分析。结果:2种药物有效率分别为76.2%、83.3%(P>0.05);治疗成本分别为1 305.00元、 588.60元。结论:丙戊酸钠缓释片治疗儿童癫痫的经济效果优于托吡酯片。

关 键 词:儿童癫痫  托吡酯片  丙戊酸钠缓释片  最小成本分析
文章编号:1001-0408(2005)21-1633-02
收稿时间:2005-08-10
修稿时间:2005-09-29

Topiramate and Sodium Valproate Retard Tablets in Treating Childhood Epilepsy: Cost- minimization Analysis
HA Li,HU Baorong,HOU Zhenhua. Topiramate and Sodium Valproate Retard Tablets in Treating Childhood Epilepsy: Cost- minimization Analysis[J]. China Pharmacy, 2005, 16(21): 1633-1634
Authors:HA Li  HU Baorong  HOU Zhenhua
Affiliation:Dept. of Pharmacy, The First Affiliated Clinical Hospital of Harbin Medical University, Harbin 150001, China
Abstract:OBJECTIVE: To explore the costs and efficacies of 2 kinds of drugs in the treatment of childhood epilepsies. METHODS: 72 children with epilepsies were assigned to receive topiramate or sodium valproate retard tablets,the efficacies of which were observed and cost-minimization analysis was conducted with the theory of pharmacoeconomics. RESULTS: The effective rates of the two drugs were 76.2% and 83.3% (P> 0.05), respectively; the costs of topiramate or sodium valproate retard tablets were 1 305.00 yuan and 588.60 yuan, respectively. CONCLUSION: Sodium valproate retard tablet is superior to topiramate tablet in terms of cost - effectiveness.
Keywords:Childhood epilepsy  Topiramate tablet  Sodium valproate retard tablet  Cost - minimization analysis
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