| 左旋咪唑与呋喃氟脲嘧啶伍用对小鼠抗肿瘤及免疫功能的影响 |
| |
| 引用本文： | 张永恒,王艳.左旋咪唑与呋喃氟脲嘧啶伍用对小鼠抗肿瘤及免疫功能的影响[J].肿瘤,1993,13(3):143-145. |
| |
| 作者姓名： | 张永恒 王艳 |
| |
| 作者单位： | 黑龙江省肿瘤医院药剂科
(张永恒，王艳)，黑龙江省肿瘤医院药剂科(吴玉波) |
| |
| 摘 要： | 本文采用呋喃氟脲嘧啶(FT-207)与增效减毒剂左旋咪唑(LMS)伍用来提高FT-207的疗效。结果伍用对小鼠S-180肉瘤的抑制作用与LMS的剂量有关,以低剂量的LMS(1mg/kg)抑瘤最佳,并能拮抗FT-207所致小鼠白细胞下降,增加小鼠胸腺和脾脏重量,促进小鼠腹腔内巨噬细胞吞噬功能,提高小鼠脾脏中NK细胞活性。
|
| 关 键 词： | 左旋咪唑 呋喃氟脲嘧啶 抗肿瘤 小鼠 |
Effect of Ftorafur Combined Levamisli on Antineoplasm and Immue Function in Mice |
| |
| Zhang Yongheng,Wan Yan,Wu Yubo Tumor Hospital of Heilongjiang Province,Harbin.Effect of Ftorafur Combined Levamisli on Antineoplasm and Immue Function in Mice[J].Tumor,1993,13(3):143-145. |
| |
| Authors: | Zhang Yongheng Wan Yan Wu Yubo Tumor Hospital of Heilongjiang Province Harbin |
| |
| Abstract: | The article reports that Ftorafur (FT-207) combined Levamisli(LMS) can incr-iease the curative effect of FT-207. The results shows that FT-207 Combined LMS onnhibition function of S180 sarcoma in mice concerns with the dosage of LMS. Low-dose LMS (1mg/kg) can increase the number of white blood cells, the weight ofthymus and spleen, the phagocytosis of macrophage and the activity of spleen NKcells in mice. |
| |
| Keywords: | Ftorafur Levamisli Antineoplasm Mice |
| 本文献已被 CNKI 维普 等数据库收录！ |
