妇肤康喷雾剂联合乳杆菌活菌胶囊治疗产后阴道炎的疗效观察

目的探讨妇肤康喷雾剂联合乳杆菌活菌胶囊治疗产后阴道炎的临床疗效。方法选取2015年1月—2017年1月郑州市第二人民医院收治的产后阴道炎患者78例,随机分为对照组和治疗组,每组各39例。对照组患者阴道深部放入阴道用乳杆菌活菌胶囊,1粒/次,1次/d。治疗组患者在对照组基础上外阴喷洒妇肤康喷雾剂,3~5揿/次,2次/d。两组均持续治疗10 d。评价两组患者临床疗效,同时比较治疗前后两组患者阴道症状、阴道p H值和复发情况。结果治疗后,对照组和治疗组的临床有效率分别为76.92%和94.87%,两组比较差异具有统计学意义(P0.05)。治疗后,两组患者p H值和阴道炎症评分较治疗前显著降低,阴道健康状况评分明显提高,同组治疗前后比较差异具有统计学意义(P0.05);且治疗后治疗组p H值和阴道炎症评分显著低于对照组,阴道健康状况评分高于对照组,两组比较差异具有统计学意义(P0.05)。治疗后,治疗组总复发率为5.13%,显著低于对照组的12.82%,两组比较差异具有统计学意义(P0.05)。结论妇肤康喷雾剂联合乳杆菌活菌胶囊治疗产后阴道炎可改善阴道局部微环境,降低复发率,具有一定的临床推广应用价值。

Clinical observation of Fufukang Spray combined with live lctobacillus cpsule in treatment of pstpartum vginitis

Objetive To investigate the clinical effect of Fufukang Spray combined with live lctobacillus cpsule in treatment of pstpartum vginitis. Methods Patients (78 cases) with pstpartum vginitis in Zhengzhou Second Hospital from January 2015 to January 2017 were randomly divided into control and treatment groups, and each group had 39 cases. Patients in the control group were vagina deeply administered with Live Lactobacillus Capsule for vaginal use, 1 grain/time, once daily. Patients in the treatment group were vulva sprayed administered with Fufukang Spray on the basis of the control group, 3-5 presses/time, twice daily. Patients in two groups were treated for 10 d. After treatment, the clinical efficacy was evaluated, and the vaginal symptoms, vaginal pH, the relapses in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 76.92% and 94.87% respectively, and there were differences between two groups (P<0.05). After treatment, the vaginal pH and vaginal inflammation symptoms score in two groups was significantly decreased, but the vaginal condition score was obviously increased, and the difference was statistically significant in the same group (P<0.05). After treatment, the vaginal pH and vaginal inflammation symptoms score in the treatment group were lower than those in the control group, but the vaginal condition score was higher than that in the control group, with significant difference between two groups (P<0.05). After treatment, the relapses rate in the treatment group was 5.13%, which was significantly lower than 12.82% in the control group, with significant difference between two groups (P<0.05). Conclusion Fufukang Spray combined with live lctobacillus cpsule in treatment of pstpartum vginitis can significantly improve vaginal microecosystem, reduce the recurrence rate, which has a certain clinical application value.