桉柠蒎肠溶软胶囊联合头孢克肟治疗老年肺炎的临床研究

目的探讨桉柠蒎肠溶软胶囊联合头孢克肟治疗老年肺炎的临床疗效。方法选取2017年2月—2017年9月在航空总医院治疗的老年肺炎患者82例,根据用药的差别分为对照组(41例)和治疗组(41例)。对照组口服头孢克肟胶囊,0.1 g/次,2次/d;治疗组在对照组基础上口服桉柠蒎肠溶软胶囊,0.3 g/次,3次/d。两组患者均经过14 d治疗。观察两组患者临床疗效,比较治疗前后两组患者临床症状评分和血清学指标。结果治疗后,对照组和治疗组的临床有效率分别为80.49%和97.56%,两组比较差异具有统计学意义(P0.05)。治疗后,两组患者咳嗽、咳痰、发热、喘息气急评分均显著降低,同组比较差异具有统计学意义(P0.05);且治疗组患者的临床症状评分明显低于对照组,两组比较差异具有统计学意义(P0.05)。治疗后,两组患者血清C反应蛋白(CRP)、降钙素(PCT)和白细胞介素-6(IL-6)水平均显著降低,同组比较差异具有统计学意义(P0.05);且治疗组血清学指标比对照组降低更显著,两组比较差异具有统计学意义(P0.05)。结论桉柠蒎联合头孢克肟胶囊治疗老年肺炎可有效改善患者临床症状,降低血清CRP、PCT和IL-6水平,具有一定的临床推广应用价值。

Clinical study on Eucalyptol, Limonene and Pinene Enteric Soft Capsules combined with cefixime in treatment of senile pneumonia

Objective To evaluate the clinical efficacy of Eucalyptol,Limonene and Pinene Enteric Soft Capsules combined with cefixime in treatment of senile pneumonia.Methods Patients (82 cases) with pneumonia in General Hospital of China Aviation from February 2017 to September 2017 were divided into control (41 cases) and treatment (41 cases) groups based on different treatment.Patients in the control group were po administered with Cefixime Capsules,0.1 g/time,twice daily.Patients in the treatment group were po administered with Eucalyptol,Limonene and Pinene Enteric Soft Capsules on the basis of the control group,0.3 g/time,three times daily.Patients in two groups were treated for 14 d.After treatment,the clinical efficacy was evaluated,and the clinical symptom scores,the serological indexes in two groups before and after treatment were compared.Results After treatment,the clinical efficacy in the control and treatment groups were 80.49% and 97.56%,respectively,and there were differences between two groups (P<0.05).After treatment,the cough,expectoration,fever,wheezing and shortness of breath scores in two groups was significantly decreased,and the difference was statistically significant in the same group (P<0.05).And these clinical symptom scores in the treatment group were significantly lower than those in the control group,with significant difference between two groups (P<0.05).After treatment,the serum CRP,PCT,but IL-6 levels in two groups were significantly decreased,and there were differences in the same group (P<0.05).And the serological indexes levels in the treatment group were significantly lower than those in the control group,with significant difference between two groups (P<0.05).Conclusion Eucalyptol,Limonene and Pinene Enteric Soft Capsules combined with cefixime in treatment of senile pneumonia can effectively improve the clinical symptoms and reduce the serum CRP,PCT,IL-6 levels,which has a certain clinical application value.