双炔失碳酯或丙睾配伍dl-15甲基PGF_(2α)抗早孕的临床比较

本文报告65例双炔失碳酯配伍d1-15甲基PGF_(2α)(以下简称PG)抗早孕结果并与33例丙睾配伍PG抗早孕结果进行比较。结果显示,双炔失碳酯组完全流产59例,占90%;不全流产3例,占5%;失败3例,占5%;总有效率95%。丙睾组完全流产27例,占82%;不全流产6例,占18%;总有效率100%。两组总有效率无显著差异;完全流产率无显著差异;但不全流产率有明显差异(P<0.05)。药流后点滴出血天数,双炔失碳酯组平均为8.1±5.0天;丙睾组平均为18.9±19.1天;两组有明显差别(P<0.05)。双炔失碳酯经阴道给药后无一例发生心、肝、肾功能变化。

A Comparison of Clinical Results of Termination of Early Pregnancy by Prostaglandin with Anordrin or Testosterone Propionate

The results of termination of early pregnancy by dl-15-methyl prostaglandin F_(2α) in combination with anordrin were compared with those by dl-15-methyl PGF_(2α) with testosterone propionate in the present study. A total of 98 early gestation women were recruited. The results show that 59 out of 65 cases were in complete abortions and 3 out of 65 cases were in incomplete, the rest being unaffected in group 1; and 27 out of 33 cases were complete abortions and the other six cases incomplete in group 2. There was significant difference between the two groups in incomplete abortions. Secondly, the daration of vaginal bleeding after evacuation of conceptus showed significant difference between two groups.