3.0T磁共振诊断直肠癌ADC值与肿瘤分化程度的相关性分析

目的通过对不同分化程度的直肠癌患者行3.0T磁共振扩散加权成像,探讨直肠癌ADC值与肿瘤分化程度的相关性及临床意义。方法对75例直肠癌患者以高、中、低度分化程度分为三组,分别行同一b值的扩散加权成像,统计各分化程度的直肠癌的ADC值,并进行单因素方差分析。结果不同分化程度的ADC值分别为低分化ADC=0.87±0.15;中分化ADC=0.96±0.15;高分化ADC=1.17±0.13;行单因素方差分析得出高分化、中分化、低分化组间差异均有统计学意义（P〈0.05）。结论不同分化程度的直肠癌的ADC值均随着肿瘤的分化程度下降而减低,两者具有相关性;临床可作为判断直肠癌的恶性程度及术后监测复发的重要指标。

Study on the relationship between ADC value and malignant degree of rectal cancer using 3.0T MR scanner

Objective To explore the relationship and clinical significance of ADC value and malignant degree in the diagnosis of rectal cancer through the diffusion weighted imaging for different malignant degree rectal cancer using 3.0T magnetic resonance imaging.Methods Divided 75 cases of rectal cancer into three group: a high,medium,low degree of differentiation,statistics and variance analysis the ADC value of the different degree of differentiation of the rectal cancer.Results The ADC values of different differentiate degree were ADC=0.87±0.15 in low differentiation,ADC=0.96±0.15 in medium differentiation and ADC=1.17± 0.13 in the high differentiation.The single factor variance analysis showed that the difference of ADC value in high differentiation,medium differentiation and low differentiation group were statistically significant(P<0.05).Conclusion The ADC value of rectal cancer decline with differentiation degree of tumour reduce,which can be used a index to evaluate the malignancy degree and postoperative recurrence in the rectal cancer.