| 2型糖尿病患者体脂与血糖、C肽的相关性分析 |
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| 引用本文： | 郭金芸,张殷殷. 2型糖尿病患者体脂与血糖、C肽的相关性分析[J]. 中国煤炭工业医学杂志, 2010, 13(4): 499-501 |
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| 作者姓名： | 郭金芸 张殷殷 |
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| 作者单位： | 广东省增城市人民医院; |
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| 摘 要： | 目的探讨2型糖尿病（T2DM）患者体脂肪量、分布与血糖、C肽分泌的关系。方法用体重脂肪测定仪测量67例T2DM患者的体脂肪率（FAT）、体脂肪含量（FATMASS）,测身高、体重、腰围（WC）、臀围,计算体重指数（BMI）、腰臀比（WHR）。作标准馒头试验和精氨酸刺激试验,分别测各时段分泌的C肽、血糖。结果患者体脂肪与血糖、HbA1c无明显相关关系（P〉0.05）;WHR与0、3h及0、2、3、5min的C肽分泌呈正相关（P〈0.05）;WC与0、1、2、3h及0、5minC肽的分泌呈正相关（P〈0.05）;BMI与0、1、2、3h及0、5minC肽的分泌呈正相关（P〈0.05）;FATMASS与0、1、2、3h及0、3、5minC肽的分泌呈正相关（P〈0.05）。多元逐步回归显示FAT与性别、腰围呈负相关（P=0）,与体脂肪含量、年龄呈正相关（P〈0.01）,影响因素多;仅与1、2h的C肽分泌呈正相关（P〈0.05）,与其他时相的C肽分泌相关性无统计学意义（P〉0.05）。结论体脂增多,尤其是腹部脂肪增多,加重T2DM患者胰岛细胞的负担,是T2DM患者胰岛素抵抗的重要危险因素。
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| 关 键 词： | 2型糖尿病 体脂 血糖 C肽分泌 |
RELATIONSHIP AMONG BODY FAT, PLASMA GLUCOSE, AND C- PEPTIDE SECRETION IN PATIENTS WITH TYPE 2 DIABETICS |
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| Guo Jinyun,Zhang Yinyin. Zengcheng People's Hospital,Guangzhou ,China. RELATIONSHIP AMONG BODY FAT, PLASMA GLUCOSE, AND C- PEPTIDE SECRETION IN PATIENTS WITH TYPE 2 DIABETICS[J]. Chinese Journal of Coal Industry Medicine, 2010, 13(4): 499-501 |
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| Authors: | Guo Jinyun Zhang Yinyin. Zengcheng People's Hospital Guangzhou China |
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| Affiliation: | Guo Jinyun,Zhang Yinyin. Zengcheng People's Hospital,Guangzhou 511300,China |
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| Abstract: | Objective To investigate the relation of body fat content,distribution with plasma glucose,and C-peptide secretion in patients with type 2 diabetics. Methods FAT,FATMASS were measured with TBF-300GS in 67 type 2 diabetic cases;Height,body weight and waist circumference were also measured to calculate BMI and WHR. Standard steamed bread test and arginine stimulate test were done in the cases to measure plasma glucose and C-peptide of every time scale. Results Body fat is not correlated with plasma glucose co... |
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| Keywords: | diabetes mellitus type 2 body fat C-peptide secretion |
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