| 羟基磷灰石/聚合物支架修复骨缺损研究进展 |
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| 引用本文： | 齐军强,陈 煜,王浩田,叶晓健,许国华.羟基磷灰石/聚合物支架修复骨缺损研究进展[J].第二军医大学学报,2023,44(11). |
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| 作者姓名： | 齐军强 陈 煜 王浩田 叶晓健 许国华 |
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| 作者单位： | 海军军医大学第二附属医院,海军军医大学第二附属医院,海军军医大学第二附属医院,上海交通大学医学院附属同仁医院,海军军医大学第二附属医院 |
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| 基金项目： | 国家自然科学基金,国家重点研发计划 |
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| 摘 要： | 羟基磷灰石/聚合物复合支架具有良好的机械性能、降解性、成骨活性、缓释功能，将其作为细胞生长因子、细胞和药物载体用于骨修复成为了骨组织工程的研究热点之一。文章主要就近几年羟基磷灰石/聚合物支架负载生长因子、细胞和药物在骨损伤或骨缺损治疗中的研究进展进行综述。
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| 关 键 词： | 羟基磷灰石 聚合物 复合支架 生长因子 载药 载细胞 骨修复 |
| 收稿时间： | 2022/10/18 0:00:00 |
| 修稿时间： | 2023/10/25 0:00:00 |
Research progress of hydroxyapatite/polymer scaffolds in repairing bone defect |
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| qijunqiang,chenyu,wanghaotian,yexiaojian and xuguohua.Research progress of hydroxyapatite/polymer scaffolds in repairing bone defect[J].Academic Journal of Second Military Medical University,2023,44(11). |
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| Authors: | qijunqiang chenyu wanghaotian yexiaojian and xuguohua |
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| Institution: | The Second Affiliated Hospital of the Naval Medical University |
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| Abstract: | Hydroxyapatite/polymer composite scaffolds have excellent mechanical properties, biodegradability, osteogenic activity, and sustained release function. Using them as cell growth factor, cells and drugs carriers for bone repair has become one of the research hotspots in bone tissue engineering. This article mainly reviews the research progress of hydroxyapatite/polymer scaffolds loaded with growth factor, cells and drugs in the treatment of bone injury or defect in recent years. |
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| Keywords: | hydroxyapatite polymer composite scaffold growth factor drug-loaded cell-loaded bone repair |
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