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Prevalence and clinical correlates of ambulatory blood pressure phenotypes in a Saudi hypertensive population
Authors:Azra Mahmud  Ruba Alahaideb  Haifa Alshammary  Mayar Abanumay  Afnan Alfawwaz  Sara Alhelabi  Amgad Alonazy  Muayed Al&#x;Zaibag
Institution:1. Hypertension Clinic, King Abdul Aziz Cardiac Center, King Abdul Aziz Medical City, National Guard Health Affairs/King Abdullah International Medical Research Center/King Saud bin Abdulaziz University for Health Sciences Riyadh, Riyadh Saudi Arabia
Abstract:International Guidelines recommend ambulatory blood pressure monitoring (ABPM) for the management of hypertension. ABPM phenotypes predict outcomes independent of office blood pressure (BP). The authors explored the prevalence and clinical correlates of ABPM phenotypes and relationship with office BP in Saudi patients (n = 428, mean age 53.5 ± 14.6, 55% male) referred to a Specialist Hypertension clinic in Riyadh, Saudi Arabia. ABPM phenotypes included sustained normotension (27%), masked hypertension, MHT(32%), sustained hypertension, SHT(52%), and white coat hypertension(2.6%). MHT was more prevalent using asleep than 24‐hours (26.4% vs 12.9%, P < .01) or awake BP (26.4% vs 8.5%, P < .001) and observed in 85% of pre‐hypertensive patients. Isolated nocturnal hypertension was more prevalent in MHT vs SHT (70% vs 30%, P < .001). Office BP overestimated control rates compared with ABPM (48% vs 12.9%, P < .001). Our study shows that one in three Saudi patients will be managed inappropriately if office BP alone was relied upon for management of hypertension.
Keywords:ambulatory blood pressure  blood pressure  blood pressure dipping  hypertension  masked hypertension  nocturnal hypertension
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