腹腔镜联合复方醋酸棉酚片治疗卵巢子宫内膜异位囊肿临床观察

目的探讨复方醋酸棉酚片治疗卵巢子宫内膜异位囊肿腹腔镜治疗术后的临床疗效。方法将89例腹腔镜下卵巢子宫内膜异位囊肿术后的患者随机分为两组:单纯腹腔镜手术组46例;复方醋酸棉酚片联合腹腔镜治疗组43例,术后口服复方醋酸棉酚片20mg/d,连续3个月。所有患者随访24个月,比较两组患者术后疗效、术后复发、妊娠及用药不良反应等情况。结果联合治疗组有效率72.09%,单纯手术组有效率39.13%,联合治疗组的疗效明显高于单纯手术组,差异有统计学意义(P0.05);联合治疗组术后复发率低于单纯手术组,差异有统计学意义(P0.05);联合治疗组术后妊娠率明显高于单纯手术组,差异有统计学意义(P0.05)。结论腹腔镜术后联合复方醋酸棉酚片治疗卵巢子宫内膜异位囊肿优于单纯手术治疗,复方醋酸棉酚片可作为卵巢子宫内膜异位症腹腔镜术后药物治疗的临床选择。

Clinical observation on treatment of ovary endometriosis with Compound Gossypol Acetate Tablets after laparoscopic surgery

Objective To investigate the role of Compound Gossypol Acetate Tablets in ovary endometriosis after laparoscopic surgery.Methods Eighty-nine women with ovary endometriosis after laparoscopic surgery were randomly divided into two groups：control group 46 cases in laparoscopic surgery only;treatment group 43 cases combined laparoscopic surgery and oral Compound Gossypol Acetate Tablets 20 mg/d after operation.All patients were followed up for 24 months.The efficacy,relapse rate,pregnancy rate and side effects were campared between the two group.Results The rate of efficiency was 72.09% in the treatment group and 39.13% in the control group.The effects of the treatment group were higher than that of the control group（P0.05）.The relapse rate in the treatment group was lower than that of the control group（P0.05）.The pregnancy rate in treatment group was significant higher than that of the control group（P0.01）.Conclusion The effects are higher in combination of laparoscopic surgery and Compound Gossypol Acetate Tablets than simple operation for the treatment of ovary endometriosis.Compound Gossypol Acetate Tablets can be used for clinical medication after laparoscopic surgery.