| 老年心肌缺血预适应延迟保护作用钝化机制的研究进展 |
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| 引用本文： | 王勇,黄从新. 老年心肌缺血预适应延迟保护作用钝化机制的研究进展[J]. 心血管病学进展, 2009, 30(3): 364-367 |
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| 作者姓名： | 王勇 黄从新 |
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| 作者单位： | 1. 卫生部中日友好医院心内科,北京,100029
2. 武汉大学人民医院心内科,湖北,武汉,430060 |
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| 摘 要： | 缺血预适应是心肌抗缺血性损伤的最有效的内源性保护机制，但是老年人缺血预适应的延迟保护作用却明显削弱甚至消失，原因和产生心肌缺血预适应延迟保护作用环节的功能下降有关，其中线粒体功能的退化和障碍最为重要。
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| 关 键 词： | 老年 心肌缺血预适应 延迟保护 钝化 |
Development on Mechanism Research of Impaired Ischemic Preconditioning' s Cardioprotection in Aged Hearts |
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| WANG Yong,HUANG Cong-xin. Development on Mechanism Research of Impaired Ischemic Preconditioning' s Cardioprotection in Aged Hearts[J]. Advances in Cardiovascular Diseases, 2009, 30(3): 364-367 |
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| Authors: | WANG Yong HUANG Cong-xin |
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| Affiliation: | WANG Yong, HUANG Cong-xin (1. Department of Cardiology, China-Japan Friendship Hospital, Beijing 100029, China; 2. Department of Cardiology,People＇s Hospital of Wuhan University, Wuhan 430060, China) |
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| Abstract: | Ischemic preconditioning protects the heart against prolonged myocardial ischemia. Delayed cardioprotection of ischemic preconditioning was impaired in aged hearts. Aging reduces the effectiveness of preconditioning mostly because of reduction of role of mitochondria in human aging. |
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| Keywords: | aged ischemic preconditioning delayed protecting impaired |
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